Introduction: At the end of 2019 a new virus, called SARS-CoV-2, emerged in Wuhan, China. The aim of the present study was to assess the impact of the first wave of the COVID-19 pandemic on the health system of the Tuscany Region and the response implemented by the South-Eastern Local Health Unit, also in view of the new reform of territorial healthcare established by Ministerial Decree No. 77 of 2022.
Methods: Data were taken from the "OpenToscana" database beginning when the first case was recorded in Italy (18 February 2020) until July 2020. We analyzed infections and deaths in each Local Heal.th Unit in the Tuscany Region and calculated the fatality rate (number of deaths/cases x 100) following COVID-19 infection. We subsequently compared the fatality rates among the Local Health Units by means of the Kruskal Wallis test.
Results: During the first wave, the South-Eastern Local Health Unit had fewer infections (a total of 1,532 by July) and fewer deaths (total: 107 by July) than the other Local Health Units. In the South-Eastern Local Health Unit, the fatality rate in July was 6.98%. The comparison of the fatality rates among the various LHUs and the whole Region showed statistically significant differences (p<0.001).
Conclusions: The organizational models promptly implemented by the South-Eastern Local Health Unit for good territorial care and the management of COVID-19-positive patients limited the spread of infection, and consequently the deaths, thus reducing the fatality rate in the first wave of the pandemic.
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http://dx.doi.org/10.7416/ai.2024.2633 | DOI Listing |
World J Surg Oncol
January 2025
Institute of Oncology, Tel Aviv Sourasky Medical Center, Weizmann St 6, Tel Aviv, Israel.
Background: De-intensification of anti-cancer therapy without significantly affecting outcomes is an important goal. Omission of axillary surgery or breast radiation is considered a reasonable option in elderly patients with early-stage breast cancer and good prognostic factors. Data on avoidance of both axillary surgery and radiation therapy (RT) is scarce and inconclusive.
View Article and Find Full Text PDFNutr J
January 2025
Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Background: Chronic kidney disease (CKD) is prevalent among elderly patients with type 2 diabetes mellitus (T2DM). The association between dietary patterns and CKD in elderly T2DM patients remains understudied. This study aimed to investigate the relationship between dietary patterns and CKD in elderly Chinese patients with T2DM.
View Article and Find Full Text PDFBMC Med Educ
January 2025
School of Nursing, Xiangnan University, 889 Chenzhou Avenue, Suxian District, Chenzhou, 423000, Hunan, People's Republic of China.
Background: In the backdrop of the ongoing global digital revolution in education, the digital literacy of teachers stands out as a pivotal determinant within the educational milieu. This study aims to explore the current status and associated factors of digital literacy among academic nurse educators.
Methods: A cross-sectional design study utilizing an online questionnaire platform (Wenjuanxing) to collect data from August to October 2023.
BMC Public Health
January 2025
Murdoch Children's Research Institute, 50 Flemington Road, Parkville, VIC, 3052, Australia.
Background: In a world confronted with new and connected challenges, novel strategies are needed to help children and adults achieve their full potential, to predict, prevent and treat disease, and to achieve equity in services and outcomes. Australia's Generation Victoria (GenV) cohorts are designed for multi-pronged discovery (what could improve outcomes?) and intervention research (what actually works, how much and for whom?). Here, we describe the key features of its protocol.
View Article and Find Full Text PDFBMC Cancer
January 2025
Department of Medical Oncology, Cancer Centre of Excellence, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Background: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with limited treatment options yielding poor outcomes. This study aimed to evaluate the real-world clinical characteristics, treatment patterns, and outcomes of patients with locally advanced unresectable and de-novo metastatic PDAC in Saudi Arabia, providing regional data to compare with international benchmarks.
Methods: This is a retrospective, multicentre study involving 350 patients diagnosed with unresectable locally advanced or de-novo metastatic PDAC between January 2015 and November 2023.
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