Background: Dextromethorphan (DXM) is an over-the-counter drug that is commonly abused by teenagers. Its main pharmacological property is a low-affinity -methyl-d-aspartate (NMDA) receptor antagonist.
Case Presentation: We report acute psychotic dissociation induced by DXM and alcohol in a patient with alcohol dependence, which made it difficult to distinguish alcohol withdrawal symptoms with limited information. The psychotic symptoms were ameliorated by haloperidol; however, in cases of DXM abuse, haloperidol treatment should be avoided.
Conclusion: In the consultation of patients with addiction, the possibility of various addictive drugs must be kept in mind. The concomitant use of DXM and alcohol causes easy dissociation and high-dose usage of DXM and alcohol withdrawal symptoms are difficult to distinguish.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450247 | PMC |
| http://dx.doi.org/10.1002/pcn5.70011 | DOI Listing |
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