AI Article Synopsis
- A case study of a 32-year-old male with a second kidney transplant revealed that herpes simplex virus-2 (HSV-2) caused both esophageal ulcers and acute graft dysfunction.
- Early diagnosis and treatment with intravenous acyclovir were crucial for recovering the kidney graft, emphasizing the need to consider rare viral infections in post-transplant care.
Article Abstract
Infections remain an important cause of morbidity in kidney transplant recipients, particularly in the early post-transplant period. This window coincides with an increased risk of acute rejections. Prompt identification of the cause of graft dysfunction is paramount to ensure good outcomes. This case report presents a 32-year-old male undergoing his second living-related kidney transplantation, complicated by herpes simplex virus-2 (HSV-2) nephritis. Despite favorable initial graft function, he developed odynophagia post-operatively, leading to the diagnosis of HSV-related esophageal ulcers. Subsequent acute graft dysfunction prompted biopsy, revealing HSV-2 related acute tubular injury. Prompt initiation of intravenous acyclovir resulted in graft recovery. This case underscores the importance of considering uncommon viral etiologies in post-transplant complications and highlights the role of timely diagnosis and treatment in preserving graft function.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450891 | PMC |
| http://dx.doi.org/10.4103/ijn.ijn_357_23 | DOI Listing |
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