The role of ketoacidotic conditions in the occurrence of diabetic angiopathies and influence of the latter on the occurrence and development of ketoacidosis in patients with diabetic vascular lesions was studied. Altogether 1152 diabetes mellitus patients were examined. It was established that abrupt fluctuations of glycemia in labile forms of diabetes with a tendency toward ketoacidosis resulted in a more noticeable vascular lesion. Diabetic nephropathy was shown to cause the development of ketoacidotic conditions as was demonstrated by a higher frequency of ketoacidosis in persons with diabetic nephropathies. The period of disease made a decisive effect on the gravity and progression of vascular lesion in diabetes mellitus.
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