Background: Multisystemic inflammatory syndrome (MIS) in the post-coronavirus disease (COVID) scenario is recognized in the pediatric population worldwide. However, no case report features jaw bone necrosis caused by self-mutilating injury noted during COVID treatment.
Case Description: This report is of a 5-year-old child affected by COVID. During the course of treatment, she presented with MIS and was treated with steroids and oxygen therapy. She was observed to have cardiac and gastrointestinal disorders. However, some psychiatric impairment caused her to pull out her lower anterior teeth, thus acting as an injury to the tissue and causing osteomyelitis. This necrotic bone tissue was excised surgically, and due to the loss of teeth, prosthetic rehabilitation was performed for the patient.
Conclusion: This unique presentation of post-COVID manifestations of self-mutilating injury is alarming for the pediatric population.
How To Cite This Article: Gala UP, Kalaskar RR. Unique Oral and Behavioral Manifestations of Post-COVID Multisystem Inflammatory Syndrome in a 5-year-old Child: A Rare Case Report. Int J Clin Pediatr Dent 2024;17(7):829-832.
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http://dx.doi.org/10.5005/jp-journals-10005-2892 | DOI Listing |
Nat Commun
December 2024
Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
Although respiratory symptoms are the most prevalent disease manifestation of infection by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), nearly 20% of hospitalized patients are at risk for thromboembolic events. This prothrombotic state is considered a key factor in the increased risk of stroke, which is observed clinically during both acute infection and long after symptoms clear. Here, we develop a model of SARS-CoV-2 infection using human-induced pluripotent stem cell-derived endothelial cells (ECs), pericytes (PCs), and smooth muscle cells (SMCs) to recapitulate the vascular pathology associated with SARS-CoV-2 exposure.
View Article and Find Full Text PDFOpen Vet J
November 2024
Zoology Department, Faculty of Science, Port Said University, Port Said, Egypt.
Background: is a member of the tilapia family that is considered one of the main food sources in different countries all over the world.
Aim: Thus, studying the different pathogens infecting tilapia species is still one of the interesting search points.
Methods: One hundred and eighty specimens of were collected from Lake Manzala and transported directly in iceboxes to the laboratory of the faculty of Science at Port Said University.
BMC Cardiovasc Disord
December 2024
Department of General Medicine, The Affiliated Hospital of Inner Mongolia Medical University, No.1, Tongdao North Road, Huimin District, Hohhot, Inner Mongolia, 010050, China.
Background: Heart failure (HF) is a syndrome with complex etiology and high mortality in the world. Macrophage-related inflammation is involved in HF development. O-GlcNAcylation is a post-translational modification that affects pathological processes.
View Article and Find Full Text PDFAm J Transplant
December 2024
Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Virol Sin
December 2024
College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China. Electronic address:
Traditional Chinese medicine has unique advantages in preventing and treating COVID-19, and Fuzheng Jiedu decoction (FZJDD) was reported to be effective against COVID-19 in clinical trials. To investigate the potential mechanisms and material basis of FZJDD against SARS-CoV-2, we performed SARS-CoV-2 target protein inhibition analyses and a metabolite full spectrum analysis of FZJDD. Interestingly, FZJDD was found to block the binding of SARS-CoV-2 Spike protein with the receptor ACE2 and inhibit the activity of SARS-CoV-2 3CLpro.
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