AI Article Synopsis
- ALS (Amyotrophic Lateral Sclerosis) is primarily a neurodegenerative disorder in adults, but a rare case of a 22-year-old Filipino male showed juvenile-onset symptoms like muscle weakness and atrophy.
- Diagnostic tests, including EMG-NCV, indicated a loss of motor neurons affecting his limbs and tongue, reinforcing the diagnosis of motor neuron disease.
- Despite treatment with riluzole and multidisciplinary care, the patient's condition worsened quickly, underscoring the difficulties in managing ALS in younger patients and the need for it to be considered in early diagnoses of motor dysfunction.
Article Abstract
Amyotrophic Lateral Sclerosis (ALS) is a rare neurodegenerative disorder primarily affecting adults, but juvenile-onset ALS is exceptionally rare. We report a rare case of a 22-year-old Filipino male patient who exhibited early-onset weakness, muscle atrophy, and tongue fasciculations, followed by rapidly progressive dysphagia and respiratory distress. Electromyography - Nerve Conduction Velocity (EMG-NCV) findings showed evidence for a chronic, active predominantly motor neuronal-axonal loss type of neuropathy involving the tongue and limb muscles bilaterally consistent with a motor neuron disease. The patient was treated with riluzole with no significant improvement in symptoms. Despite multidisciplinary interventions, the disease rapidly progressed, highlighting the challenges in managing juvenile ALS cases. This case report emphasizes the importance of considering ALS in the differential diagnosis of progressive motor dysfunction in younger patients and the complexities involved in their care.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11449882 | PMC |
| http://dx.doi.org/10.7759/cureus.68579 | DOI Listing |
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