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Genome-wide identification of the WOX gene family in Populus davidiana×P.bolleana and functional analysis of PdbWOX4 in salt resistance.
Plant Sci
December 2024
State Key Laboratory of Tree Genetics and Breeding (Northeast Forestry University), Harbin 150040, China. Electronic address:
WOX transcription factors (TFs) are plant specific transcription regulatory factors that have a momentous role in maintaining plant growth and development and responding to abiotic stress. In this study, a total of 13 PdbWOX genes were identified. qRT-PCR analyses showed that 13 PdbWOX genes were responsive to salt stress.
View Article and Find Full Text PDFMomentous Times for Social Needs Screening: Should Hospitalists Ride the Tide or Create the Waves?
Hosp Pediatr
November 2024
Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Recent advancements toward the incremsent of drug solubility using environmentally-friendly supercritical CO: a machine learning perspective.
Front Med (Lausanne)
September 2024
Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Inadequate bioavailability of therapeutic drugs, which is often the consequence of their unacceptable solubility and dissolution rates, is an indisputable operational challenge of pharmaceutical companies due to its detrimental effect on the therapeutic efficacy. Over the recent decades, application of supercritical fluids (SCFs) (mainly SCCO) has attracted the attentions of many scientists as promising alternative of toxic and environmentally-hazardous organic solvents due to possessing positive advantages like low flammability, availability, high performance, eco-friendliness and safety/simplicity of operation. Nowadays, application of different machine learning (ML) as a versatile, robust and accurate approach for the prediction of different momentous parameters like solubility and bioavailability has been of great attentions due to the non-affordability and time-wasting nature of experimental investigations.
View Article and Find Full Text PDFSeptic shock in the immunocompromised cancer patient: a narrative review.
Crit Care
August 2024
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, 200 First Street S.W., Rochester, MN, 55905, USA.
Article Synopsis
- Many cancer patients and people with weakened immune systems face a higher risk of serious infections because their bodies can't fight germs as well.
- Factors like age, other health problems, and the type and stage of cancer can make them even more vulnerable to severe conditions like septic shock.
- To improve survival rates, it's important to quickly identify infections and provide specialized care, using new technologies and teamwork among healthcare providers.
Endonasal endoscopic or endoscopic-assisted transcranial surgery of Rathke's cleft cysts: does the approach and surgical technique influence the radicality and recurrence rate?
Neurosurg Rev
August 2024
Department of Neurosurgery, Faculty of Medicine, Saarland University Medical Center and Saarland University, Homburg, Germany.
Objective: Resections of symptomatic Rathke's cleft cysts (RCCs) are mainly performed via an endonasal transsphenoidal approach. However, there is a lack of equivalent data in current literature concerning transcranial keyhole approach in the treatment of RCCs. In order to find general recommendations for the surgical treatment of RCCs also with regard to recurrence, the object of this study is the analysis and comparison of both techniques.
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