AI Article Synopsis

  • Detrusor muscle weakness is a common problem that makes it hard for people to urinate, and there's no proven way yet to make the muscle stronger.
  • Experts discussed this issue at a meeting in Bristol and looked at various treatments like electrical stimulation, surgery for bladder problems, and ways to help with constipation.
  • Although some treatments may help patients feel better, there's not enough strong evidence showing they actually make the detrusor muscle stronger, so more research is needed.

Article Abstract

Introduction: Detrusor muscle weakness is commonly noted on urodynamics in patients with refractory voiding difficulty. No clinical therapy has been proven to augment the strength of a detrusor contraction.

Methods: This subject was discussed at a think-tank at the International Consultation on Incontinence-Research Society (ICI-RS) held in Bristol, June 2024. The discussions of the think-tank are being published in two parts. This second part discusses the role of electrical stimulation therapies, treatment of bladder outlet obstruction, constipation, and pelvic floor disorders, in the enhancement of strength of a detrusor contraction.

Results: Electrical stimulation therapies, specifically sacral neuromodulation, have long been used in the salvage of patients with refractory nonobstructive voiding dysfunction. Clinical improvements can be noted in men following bladder outlet resistance reduction surgery especially, though not limited to those with demonstrable obstruction. Some patients may also show improvement with pelvic floor relaxation therapies and constipation care. However, there is a lack of high-quality urodynamic data to demonstrate an improvement in the strength of a detrusor contraction with these therapies. The think-tank recommends standards for future clinical studies examining treatments aimed at improving an underactive detrusor.

Conclusions: Studies need to examine whether clinical improvement following treatment of patients with an underactive detrusor is associated with improvement in strength of the detrusor contraction. New therapeutic options should apply specified standards for assessing and reporting the impact on detrusor contraction.

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http://dx.doi.org/10.1002/nau.25594DOI Listing

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Introduction: Detrusor muscle weakness is commonly noted on urodynamics in patients with refractory voiding difficulty. No approved therapies have been proven to augment the strength of a detrusor voiding contraction.

Methods: This subject was discussed by a think-tank at the International Consultation on Incontinence- Research Society (ICI-RS) meeting held in Bristol, June 2024.

View Article and Find Full Text PDF
Article Synopsis
  • Detrusor muscle weakness is a common problem that makes it hard for people to urinate, and there's no proven way yet to make the muscle stronger.
  • Experts discussed this issue at a meeting in Bristol and looked at various treatments like electrical stimulation, surgery for bladder problems, and ways to help with constipation.
  • Although some treatments may help patients feel better, there's not enough strong evidence showing they actually make the detrusor muscle stronger, so more research is needed.
View Article and Find Full Text PDF

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