AI Article Synopsis
- A 54-year-old woman experienced persistent fatigue and high fever, leading to the discovery of central pontine myelinolysis (CPM) on brain scans, even though she had no neurological symptoms.
- Investigation revealed she had primary splenic diffuse large B-cell lymphoma (PS-DLBCL), with her low serum sodium being a contributing factor.
- The CPM condition was treated successfully through splenectomy and immunochemotherapy, marking the first documented case of CPM linked to PS-DLBCL with pathology confirmation and improvements noted in brainstem auditory-evoked potentials.
Article Abstract
A 54-year-old woman with persistent fatigue and a high fever presented with central pontine myelinolysis (CPM) on brain imaging, despite the absence of neurological symptoms. The patient had a slightly low serum sodium concentration. Further investigation led to a diagnosis of primary splenic diffuse large B-cell lymphoma (PS-DLBCL). Brainstem auditory-evoked potentials (BAEP) indicated minor abnormalities. CPM was successfully resolved after splenectomy and immunochemotherapy. This is the first reported case of CPM in a patient with PS-DLBCL confirmed by a pathological diagnosis following splenectomy and BAEP-detected abnormalities that improved with immunochemotherapy.
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| http://dx.doi.org/10.2169/internalmedicine.3926-24 | DOI Listing |
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