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| http://dx.doi.org/10.1111/srt.70067 | DOI Listing |
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Tricuspid valve edge-to-edge repair simulations are highly sensitive to annular boundary conditions.
J Mech Behav Biomed Mater
December 2024
Department of Mechanical Engineering, The University of Texas at Austin, 204 E. Dean Keeton Street, Austin, TX, 78712, USA; Department of Aerospace Engineering & Engineering Mechanics, The University of Texas at Austin, 2617 Wichita Street, Austin, TX, 78712, USA; Department of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton Street, Austin, TX, 78712, USA; The Oden Institute for Computational Engineering & Sciences, The University of Texas at Austin, 201 E. 24th Street, Austin, TX, 78712, USA. Electronic address:
Transcatheter edge-to-edge repair (TEER) simulations may provide insight into this novel therapeutic technology and help optimize its use. However, because of the relatively short history and technical complexity of TEER simulations, important questions remain unanswered. For example, there is no consensus on how to handle the annular boundary conditions in these simulations.
View Article and Find Full Text PDF[Transthoracic cardiac ultrasonic shear wave elastography for detecting myocardial stiffness in healthy and hypertrophic cardiomyopathy individuals].
Zhonghua Yi Xue Za Zhi
November 2024
Heart Failure Care Unit, Heart Failure Center, Fuwai Hospital, Chinese Academy of Medical Sciences, National Center for Cardiovascular Diseases, Beijing100037, China.
To explore the feasibility of transthoracic cardiac shear wave elastography (SWE) for non-invasive quantitative measurement of myocardial stiffness in healthy volunteers (HV) and hypertrophic cardiomyopathy (HCM) patients, and analyze the relationship between myocardial shear wave velocity (SWV) and left ventricular diastolic function. A total of 16 HV who underwent health check-ups and 5 HCM patients who visited the Cardiology Outpatient Clinic at Fujian Medical University Affiliated Union Hospital from September 2022 to October 2023 were prospectively recruited. The SWE technique was used to measure SWV of the basal segment of the interventricular septum, including left ventricular long-axis myocardial shear wave velocity (LA-SWV) and short-axis myocardial shear wave velocity (SA-SWV).
View Article and Find Full Text PDFMulti-acquisition multi-resolution full-waveform shear wave elastography for reconstructing tissue viscoelasticity.
Phys Med Biol
December 2024
North Carolina State University, Raleigh, NC, United States of America.
. Motivated by the diagnostic value of tissue viscosity beyond elasticity, the goal of this work is to develop robust methodologies based on shear wave elastography (SWE) to reconstruct combined elasticity and viscosity maps of soft tissues out of the measurement plane.Building on recent advancements in full-waveform inversion in reconstructing elasticity maps beyond the measurement plane, we propose to reconstruct a complete viscoelasticity map by novel combination of three ideas: (a) multiresolution imaging, where lower frequency content is used to reconstruct low resolution map, which is then utilized as a starting point for higher resolution reconstruction by including higher frequency content; (b) acquiring SWE data on multiple planes from multiple pushes, one at a time, and then simultaneously using all the data to invert for a single viscoelasticity map; (c) sequential reconstruction where combined viscoelasticity reconstruction is followed by fixing the elasticity map (and thus kinematics), and repeating the reconstruction but just for the viscosity map.
View Article and Find Full Text PDFFava Bean Protein Nanofibrils Modulate Cell Membrane Interfaces for Biomolecular Interactions as Unveiled by Atomic Force Microscopy.
Foods
October 2024
Leibniz Institute for Food Systems Biology at the Technical University of Munich, Lise-Meitner-Str. 34, 85354 Freising, Germany.
Functional amyloids (protein nanofibrils, PNF) synthesized from plant sources exhibit unique physicochemical and nanomechanical properties that could improve food texture. While environmental factors affecting PNFs are well-known, scientific evidence on how cells (focus on the oral cavity) respond to them under physiological conditions is lacking. Self-assembled PNFs synthesized from fava bean whole protein isolate show a strong pH- and solvent-dependent morphology and elasticity modification measured by atomic force microscopy (AFM).
View Article and Find Full Text PDFFront-Tracking and Gelation in Sessile Droplet Suspensions: What Can They Tell Us about Human Blood?
Biomacromolecules
December 2024
Institute for Energy and Environmental Flows, University of Cambridge, Bullard Laboratories, Madingley Road, Cambridge, CB3 0EZ, United Kingdom.
Recently developed imaging techniques have been used to examine the redistribution of human red blood cells and comparator particles dispersed in carrier fluids within evaporating droplets. We demonstrate that progressive gelation initiates along an annular front, isolating a central pool that briefly remains open to particulate advection before gelation completes across the droplet center. Transition to an elastic solid is evidenced by cracking initiating proximal to front locations.
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