PKM2-G-quadruplex interactions conspire to regulate the cancer transcriptome.

Mol Cell

Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

Published: October 2024

In this issue of Molecular Cell, Anastasakis et al. describe a novel function of the metabolic enzyme PKM2 as an RNA G-quadruplex binding protein, which could contribute to cancer biology.

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Source
http://dx.doi.org/10.1016/j.molcel.2024.09.013DOI Listing

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