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Airway basal stem cell therapy for lung diseases: an emerging regenerative medicine strategy.
Stem Cell Res Ther
January 2025
Department of Pulmonary and Critical Care Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Chronic pulmonary diseases pose a prominent health threat globally owing to their intricate pathogenesis and lack of effective reversal therapies. Nowadays, lung transplantation stands out as a feasible treatment option for patients with end-stage lung disease. Unfortunately, the use of this this option is limited by donor organ shortage and severe immunological rejection reactions.
View Article and Find Full Text PDFAlzheimer's disease: an integrative bioinformatics and machine learning analysis reveals glutamine metabolism-associated gene biomarkers.
BMC Pharmacol Toxicol
January 2025
Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, 264100, PR China.
Background: Alzheimer's disease (AD), a hallmark of age-related cognitive decline, is defined by its unique neuropathology. Metabolic dysregulation, particularly involving glutamine (Gln) metabolism, has emerged as a critical but underexplored aspect of AD pathophysiology, representing a significant gap in our current understanding of the disease.
Methods: To investigate the involvement of GlnMgs in AD, we conducted a comprehensive bioinformatic analysis.
Experiences, perceptions and ethical considerations of the malaria infection study in Thailand.
BMC Med Ethics
January 2025
Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Thunphayathai, Bangkok, 10400, Thailand.
Background: Thailand has made significant progress in malaria control efforts in the past decade, with a decline in the number of reported cases. However, due to cross-border movements over the past 5 years, reported malaria cases in Thailand have risen. The Malaria Infection Study in Thailand (MIST) involves deliberate infection of healthy volunteers with Plasmodium vivax malaria parasites, and the assessment of the efficacy of potential vaccine and drug candidates in order to understand acquired protection against malaria parasites.
View Article and Find Full Text PDFSecular trends of physical fitness for college students in Anhui Province over the past decade.
BMC Public Health
January 2025
School of Physical Education, Chizhou University, Chizhou, 247000, China.
Background: Since the beginning of the 21st century, China's economy has experienced rapid growth, resulting in a steady improvement in its citizens' living standards. However, alongside the emergence of modern civilization-related health issues, the overall physical fitness of the population has been declining. In the final year of 2019, a global COVID-19 pandemic emerged and persisted for three years, causing a significant diminution in human physical well-being.
View Article and Find Full Text PDFExploring factors of physicians' preferences for continuing medical education.
BMC Med Educ
November 2024
Faculty of Health Sciences, Bielefeld University, Bielefeld, Germany.
Background: Achieving sustainability in continuing medical education (CME) involves regular assessment of the evolving needs of healthcare professionals regarding their competencies and updates in educational content accordingly. This study aimed to investigate the key areas and competencies that physicians in Serbia prioritize for their professional development and to analyze the factors associated with these competencies.
Method: This cross-sectional study was conducted among 2,625 physicians who are members of the medical chamber in Serbia.
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