AI Article Synopsis
- * Severe viral infections can increase the risk of developing pediatric OSA, which is often caused by enlarged adenoids and tonsils.
- * The review explores how respiratory viruses affect the development of upper airway lymphoid tissues and the relationship between OSA and viral infections, emphasizing the need for monitoring and new prevention strategies.
Article Abstract
Obstructive sleep apnea (OSA) and viral respiratory infections are highly prevalent conditions in children and a major cause of respiratory morbidity in this age group. Severe viral respiratory infections are a known risk factor for pediatric OSA, which is primarily caused by hypertrophy of upper airway lymphoid tissues (adenoids and tonsils). This review examines recent progress in understanding early-life development of lymphoid tissues in the human upper airway, with a particular focus on how respiratory viruses may influence this process and contribute to OSA pathogenesis. It also explores the bidirectional relationship between OSA and severe viral infections, highlighting the need for ongoing monitoring and novel primary prevention strategies to address these interconnected conditions.
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| http://dx.doi.org/10.1002/ppul.27314 | DOI Listing |
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