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How Quickly Multiple Medication Use Can Start: A Medication for Every Complaint on the First Visit Compromising the Ability to Determine Cause and Effect.
J Psychiatr Pract
January 2025
Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Kansas, Wichita, KS.
This article presents a case demonstrating that multiple medication use can begin on the first outpatient visit if the prescriber makes multiple psychiatric diagnoses and then feels the need to treat each diagnosis with a different central nervous system active medication labeled for each indication. This approach poses potential problems. First, a single drug or perhaps 2 drugs, in this case, may have been sufficient as initial and perhaps final treatment.
View Article and Find Full Text PDFThe role of serendipity in our investigation of embryo implantation.
Dev Biol
January 2025
Department of Cell Biology, University of Virginia Health System, PO Box 800732 Charlottesville, VA 22908-0732. Electronic address:
Serendipity plays a huge role in science, and having a prepared mind that can seize upon a serendipitous observation or occurrence can drive a project forward. This happened in my lab with a project centered on the regulation of trophoblast cell behavior at implantation. We discovered that amino acids regulate the onset of trophoblast motility through the activation of the kinase complex mTORC1, and that this acts as a checkpoint to trophoblast differentiation.
View Article and Find Full Text PDFThought-Feeling Accuracy in Person Perception and Metaperception: An Integrative Perspective.
Annu Rev Psychol
January 2025
Department of Psychology, Northeastern University, Boston, Massachusetts, USA.
People often want to know what their interaction partners are thinking. How accurate are they, what information do they use, what predicts how accurate they will be, and does accuracy matter? We organize our review of thought-feeling accuracy, defined as the accuracy of individuals' judgments about the content of another person's thoughts and feelings in live interaction, around these questions. At the same time, we argue that often people are especially interested in what others are thinking about them, such that research on the accuracy of individuals' metaperceptions regarding others' views of them is highly relevant to understanding thought-feeling accuracy more broadly construed.
View Article and Find Full Text PDFMikhail 'Misha' Blagosklonny's enduring legacy in geroscience: the hyperfunction theory and the therapeutic potential of rapamycin.
Aging (Albany NY)
January 2025
Geneva College of Longevity Science, Geneva 1204, Switzerland.
The untimely passing of Dr. Mikhail "Misha" Blagosklonny has left a lasting void in geroscience and oncology. This review examines his profound contributions, focusing on his pioneering the Hyperfunction Theory and his advocacy for rapamycin, an mTOR inhibitor, as a therapeutic agent for lifespan extension.
View Article and Find Full Text PDFUnited Nations, the Struggle for Gender Equity, and Queering Global Science.
OMICS
January 2025
OMICS: A Journal of Integrative Biology, New Rochelle, New York, USA.
UN Women is the United Nations "entity dedicated to gender equality and the empowerment of women". UN Women is an example of the institutions of global governance that followed the gender turn in women's rights over the past 2 decades. This opinion commentary unpacks a brief history of UN Women, and the ongoing disparities in gender diversity, equity, and inclusion (DEI) in science, engineering, and medicine, not to mention in science communication, with the aim to shed light on the adverse impacts of gender essentialism and gender binary.
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