Alcohol-Associated Liver Diseases: Spectrum, Nomenclature, and Definitions.

Clin Liver Dis

Department of Hepatology, Institute of Liver and Biliary Sciences, Sector D1, Vasantkunj, New Delhi 110070, India. Electronic address:

Published: November 2024

Alcohol-associated liver disease (AALD) is a global health problem with increasing incidence with associated high morbidity and mortality. Patients with AALD have varied clinical presentation encompassing a spectrum ranging from alcoholic steatosis, alcoholic steatohepatitis to alcohol-associated fibrosis/cirrhosis, which can be either compensated or decompensated. We need uniformity in defining each of the stages of AALD, which will help in both research and patient care. Algorithmic approach using noninvasive tests like enhanced liver fibrosis score, elastography, and fibrosis-4 scores can help in early diagnosis in addition to the presence of any red flags (low albumin, low platelet count, and raised transaminases).

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Source
http://dx.doi.org/10.1016/j.cld.2024.06.003DOI Listing

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