Diagnosis and Management of Inflammatory Bowel Disease-Associated Spondyloarthritis.

Am J Gastroenterol

Department of Gastroenterology, Hepatology and Nutrition, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Published: January 2025

AI Article Synopsis

  • Inflammatory bowel disease (IBD)-associated spondyloarthritis (SpA) is a common but complex condition that needs better understanding and management strategies.
  • For diagnosing IBD-associated peripheral SpA (IBD-pSpA), collaboration with rheumatology is crucial for evaluating symptoms, physical exams, and imaging.
  • Treatment should start with addressing the underlying IBD activity and may include advanced therapies, with a similar collaborative approach recommended for diagnosing and managing axial SpA (IBD-axSpA), using targeted medications as necessary.

Article Abstract

Inflammatory bowel disease (IBD)-associated spondyloarthritis (SpA) is common but remains poorly understood. In this review article, we aimed to provide guidance regarding the diagnosis and management of this condition. For diagnosis of IBD-associated peripheral SpA (IBD-pSpA), we recommend collaboration with rheumatology for incorporation of clinical symptoms, physical examination findings, joint imaging if applicable, and available diagnostic criteria. For the management of IBD-pSpA, we first recommend assessment and treatment of underlying luminal IBD disease activity. We provide guidance regarding positioning of advanced therapies for IBD in patients with IBD-pSpA based on the limited available literature. For diagnosis of IBD-associated axial SpA, we recommend rheumatology referral to make the diagnosis based on incorporation of symptoms, laboratory data, imaging findings (sacroiliitis), and available diagnostic criteria. For the management of axial SpA, we recommend comanagement with rheumatology and use of either antitumor necrosis factor agents or Janus kinase inhibitors, when applicable.

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http://dx.doi.org/10.14309/ajg.0000000000003092DOI Listing

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