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Generative dynamical models for classification of rsfMRI data.
Netw Neurosci
December 2024
Department of Psychology, Stanford University, Stanford, CA, USA.
The growing availability of large-scale neuroimaging datasets and user-friendly machine learning tools has led to a recent surge in studies that use fMRI data to predict psychological or behavioral variables. Many such studies classify fMRI data on the basis of static features, but fewer try to leverage brain dynamics for classification. Here, we pilot a generative, dynamical approach for classifying resting-state fMRI (rsfMRI) data.
View Article and Find Full Text PDFUnveiling the hidden causal links: skin flora and cutaneous melanoma.
Front Oncol
December 2024
Department of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Objective: The presence of skin flora (SF) has been identified as a significant factor in the onset and progression of cutaneous melanoma (CM). However, the vast diversity and abundance of SF present challenges to fully understanding the causal relationship between SF and CM.
Methods: A Two Sample Mendelian Randomization (TSMR) analysis was conducted to investigating the causal relationship between SF and CM.
The Implementation and Outcomes of Personalized Antihypertensive Therapy Based on Pharmacogenetic Testing: A Retrospective Study Examining Blood Pressure Control and Medication Tolerability.
Cureus
November 2024
Medicine Department, Khyber Medical University, Peshawar, PAK.
Background: Hypertension management typically relies on standardized treatment regimens, which may not account for individual genetic variations that affect drug metabolism and response.
Objective: The objective of this study was to evaluate the effectiveness of personalized antihypertensive therapy, guided by pharmacogenetic testing, in terms of blood pressure (BP) control and medication tolerability.
Materials And Methods: A retrospective cohort study was conducted at Jinnah Postgraduate Medical Centre, Karachi, from January 2023 to December 2023.
Collaborative ethnography and a call for pluralism and dialogic knowledge in health equity debates and global cancer research culture.
Anthropol Med
December 2024
Gino Germani Research Institute (IIGG), Faculty of Social Sciences, University of Buenos Aires (UBA) and National Council of Scientific and Technological Research (CONICET), Buenos Aires, Argentina.
Scholars in medical anthropology note that, despite more than 25 years of anthropological studies on cancer, much of this scholarship remains marginal in mainstream public health approaches. This paper examines social practices, biases, and unnoticed assumptions in mainstream global health research culture that prevents anthropology from having a more influential role in cancer research and policy agendas. It focuses on the day-to-day, ordinary, micro academic practices in which differential power distribution exacerbates inequity within the field, ignoring the role played by approaches with disciplinarian, epistemological and geopolitical peripheries.
View Article and Find Full Text PDFCharacterization of neuronal oscillations in the prelimbic cortex, nucleus accumbens and CA1 hippocampus during object retrieval task in rats predisposed to early life stress.
Behav Brain Funct
December 2024
Department of Neurophysiology, National Institute of Mental Health and Neuro Sciences, Bengaluru, 560 029, India.
Background: Early life stress (ELS) during the stress hypo-responsive period (SHRP) alters the curiosity-like behavior later during adolescence. Previous studies have shown maternal separation (MS) stress-induced heightened curiosity and associated risk-taking behavior in the object retrieval task (ORT). However, the neural correlates of curiosity in adolescent rats predisposed to early life stress remain unexplored.
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