Unusual manifestation of synovial sarcoma: A rare case report with elevated beta HCG level.

Radiol Case Rep

Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Published: November 2024

AI Article Synopsis

  • Synovial sarcoma is a rare type of cancer that usually grows in the lower part of the body, but this case involves a man with symptoms like shortness of breath and pain who had a lump in his wrist.
  • The man also had gynecomastia (breast tissue growth in men) and high levels of a hormone called βHCG, which indicated there was something unusual happening in his body.
  • The article wants to teach doctors that they should consider synovial sarcoma when they see certain symptoms or hormonal changes so they can catch it early and help avoid more serious problems.

Article Abstract

Synovial sarcoma is a rare type of soft tissue sarcoma that typically arises in the lower extremities and rarely in the upper extremities. Here, we present an unusual case of a middle-aged man who complained of dyspnea, dry cough, and chest pain and was found to have a mass-like lesion on the ulnar side of his left wrist during physical examination. The patient also exhibited gynecomastia and had elevated β-human chorionic gonadotropin (βHCG) levels. Subsequent imaging and histopathological analysis of the wrist mass confirmed the diagnosis of synovial sarcoma with disseminated lung metastasis. This article aims to provide a comprehensive overview of the clinical and pathological characteristics of synovial sarcoma, highlight the importance of considering synovial sarcoma as a differential diagnosis in patients with abnormal hormonal assays, and emphasize the need for clinicians to be vigilant about any pathologic lesions existing on the upper extremity to avoid late diagnosis and the development of advanced cancerous diseases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11445589PMC
http://dx.doi.org/10.1016/j.radcr.2024.07.178DOI Listing

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