AI Article Synopsis
- Corticosteroids, although effective in treating inflammation and modifying immune responses, can lead to several side effects like high blood sugar, hypertension, and bradycardia (slow heart rate).
- A case study details a 43-year-old woman with multiple sclerosis who developed symptomatic bradycardia after receiving high doses of methylprednisolone, which resolved after 36 hours once the medication was stopped.
- While bradyarrhythmias like bradycardia are rare compared to tachyarrhythmias, they are important to monitor, and corticosteroid-induced bradycardia typically resolves on its own and often occurs without clear reasons.
Article Abstract
Introduction: Besides their wide use in the clinical field due to their anti-inflammatory and immune-modulating effect, corticosteroids still have a lot of adverse effects. The most common adverse effects are hyperglycemia, hypertension, osteoporosis, psychosis, immunosuppression, weight gain, and hyperlipidemia. Another important side effect is cardiac arrhythmias.
Case Presentation: We report a case of a 43-year-old woman with multiple sclerosis who developed symptomatic bradycardia after 3 days of treatment with a high dose of methylprednisolone. The patient received a dose of atropine and her bradycardia resolved after 36 h of stopping methylprednisolone.
Discussion: While tachyarrhythmias are more common, bradyarrhythmias such as bradycardia and premature atrial or ventricular contraction are rare but crucial to be considered.
Conclusion: Corticosteroid-induced bradycardia is usually in sinus rhythm and has an unknown etiology, possibly occurring at high and low doses. The majority of cases in the literature were asymptomatic and resolved spontaneously.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444592 | PMC |
| http://dx.doi.org/10.1097/MS9.0000000000002530 | DOI Listing |
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Article Synopsis
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