Purpose: This study aimed to evaluate the effect of intraoperative positioning and ocular immobility on the amount of cerebrospinal fluid around the optic nerve in patients undergoing prone spinal surgery by measuring the optic nerve sheath diameter (ONSD) using ultrasound.
Methods: Consecutive participants ( = 15 patients, 30 eyes) were scanned preoperatively, intraoperatively approximately 20 minutes before the end of the surgery, and postoperatively in the post-anesthesia care unit at least 10 min after the completion of the surgery at one academic hospital.
Results: On average, patients who underwent prone spinal surgery had a 21% increase in ONSD intraoperatively, with a positive time-dependent relationship with the overall length of surgery ( 0.001). ONSDs postoperatively returned to baseline and were not significantly different from preoperative measurements.
Conclusion: Our findings suggest pooling and inadequate clearance of perioptic cerebrospinal fluid during prone spinal surgery that improves following termination of the procedure and return of the patient to an upright position.
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http://dx.doi.org/10.18502/jovr.v19i3.13863 | DOI Listing |
Vet Res Commun
January 2025
Department of Biomaterials and Medical Devices Engineering, Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta 40, Zabrze, 41-800, Poland.
Chronic instability at the lumbosacral junction, particularly between the L7 vertebra and the sacral bone, presents significant challenges in veterinary orthopedics, especially for large breed dogs. This condition frequently results in severe pain, neurological deficits, and mobility impairments, prompting the development of various surgical techniques aimed at effectively stabilizing the affected area. A critical evaluation of the literature on surgical stabilization of the lumbosacral spine in dogs reveals the clinical applications, outcomes, and future directions in veterinary spinal surgery.
View Article and Find Full Text PDFEur Spine J
January 2025
Aix-Marseille University, CNRS, CRMBM, Marseille, France.
Background And Purpose: Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord (SC) dysfunction. In routine clinical practice, SC changes are well depicted using conventional MRI, especially T2-weighted imaging. However, this modality usually fails to provide satisfactory clinico-radiological correlations.
View Article and Find Full Text PDFObjective: To investigate the value of routine T2-weighted magnetic resonance imaging (MRI) and contrast-enhanced magnetic resonance angiography (CE-MRA) sequences in locating the fistula level of spinal arteriovenous fistula (SAVF).
Methods: Retrospectively analyzed the radiological findings of patients with SAVF diagnosed by surgery from May 2018 to September 2024. All patients completed spinal CE-MRA and routine T2-weighted MRI.
Acta Orthop
January 2025
Department of Orthopaedics and Hand Surgery, Uppsala University Hospital, Uppsala; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Background And Purpose: Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord dysfunction in adults. Repeated follow-ups after surgery are resource consuming. The aim was to examine whether patient-reported outcome measures (PROMs) change after the first year.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Background: As blood-based biomarkers become critical to Alzheimer's Disease (AD) clinical testing, establishment of less invasive plasma collection methods are key. We compared the Tasso+ and the TAPII capillary whole blood collection devices to traditional venipuncture for safety and efficacy in our clinic and measured AD biomarkers neurofilament-light (NFL), glial fibrillary acidic protein (GFAP), phosphorylated-tau 217 (ptau217), and amyloid-beta 42/40 ratio (Aβ42/40) in cerebrospinal fluid (CSF), capillary, and venous plasma to assess potential age and cognition related group differences.
Method: Patients seen at the Johns Hopkins Center for CSF Disorders (N = 193) underwent diagnostic lumbar punctures and/or extended lumbar drainage procedures.
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