AI Article Synopsis
- - Granulomatosis with polyangiitis (GPA) is a rare vasculitis that primarily impacts small to medium blood vessels, often affecting the airways and kidneys.
- - Cardiac involvement in GPA is uncommon and typically doesn't present as the first symptom, making this case noteworthy.
- - A 44-year-old man experienced a heart issue that led to the diagnosis of GPA, showcasing vasculitis in the coronary arteries and myocarditis; he was treated with steroids, rituximab, and avacopan.
Article Abstract
Granulomatosis with polyangiitis (GPA) is a rare type of small to medium vessel necrotizing vasculitis that usually affects vessels of the upper or lower airways and kidneys. Cardiac involvement in GPA is often subclinical and if clinically significant has been rarely reported, even less so as an initial presentation. We describe the case of a 44-year-old man who presented with what appeared to be inferior ST-segment elevation myocardial infarction and was found to have small vessel vasculitis of the coronary arteries with associated myocarditis as a presenting manifestation of GPA, which was ultimately treated with steroids, rituximab, and avacopan.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11442193 | PMC |
| http://dx.doi.org/10.1016/j.jaccas.2024.102499 | DOI Listing |
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