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Efficacy of uterine flushing with human chorionic gonadotropin (hCG) on pregnancy rates in primary unexplained infertility: a randomized controlled trial.
Eur J Med Res
December 2024
Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: There are limited and controversial findings concerning ovulation induction using intrauterine and intramuscular human chorionic gonadotropin (hCG) injection compared to intramuscular hCG alone. The study aimed to examine the impact of intrauterine hCG injection, which is used to induce ovulation, on the efficacy of the intrauterine insemination (IUI) technique in patients with unexplained infertility.
Methods: A randomized controlled clinical trial was conducted involving 80 subjects with unexplained primary infertility at the infertility clinic of Al-Zahra Hospital in northwest Iran.
Collaborative study for the establishment of Golimumab Biological Reference Preparation Batch 1.
Pharmeur Bio Sci Notes
December 2024
European Directorate for the Quality of Medicines & HealthCare, Department of Biological Standardisation, OMCL Network & HealthCare (DBO), Council of Europe, Strasbourg, France.
A candidate preparation of the fully human anti-tumour necrosis factor (TNF) monoclonal antibody golimumab was formulated and lyophilised at the Medicines and Healthcare products Regulatory Agency (MHRA) prior to evaluation in a collaborative study for its suitability to serve as a World Health Organization (WHO) International Standard (IS)/European Pharmacopoeia (Ph. Eur.) Biological Reference Preparation (BRP) for the potency assay of golimumab.
View Article and Find Full Text PDFInvestigation of In Situ Gelation Behavior and Enhanced Oil Recovery Ability of Polymer Gel Used for Controlling CO Channeling in Tight Fractured Reservoir.
Gels
November 2024
College of Earth Science and Resources, Chang'an University, Xi'an 710100, China.
Article Synopsis
- * This study examines the gelation behavior of crosslinked phenolic resin gel using a stainless microtube to simulate fractured porous media, finding that higher polymer and crosslinker concentrations lead to stronger gels and faster gelation times.
- * Results indicate that static gelation occurs more quickly in the microtube compared to bulk gelation, and increasing polymer concentration enhances oil recovery, with a notable increase from 3.53% to 4.73% as concentration rises from 3000 mg·L to 4000 mg·L.
Topical Vitamin D Derivative (Calcipotriol) Versus Intralesional Vitamin D in the Treatment of Cutaneous Warts: A Clinical Therapeutic Comparative Trial.
Dermatol Res Pract
November 2024
Department of Dermatology, Basrah Medical College, University of Basrah, Basra, Iraq.
Cutaneous warts are epidermal proliferations caused by human papillomavirus. There are a variety of treatment options for warts with different success rates. Intralesional vitamin D injection is an innovative treatment option for warts, and several studies have examined its efficacy.
View Article and Find Full Text PDFSilk-hydrogel functionalized with human decellularized Wharton's jelly extracellular matrix as a minimally invasive injectable hydrogel system for potential nucleus pulposus tissue replacement therapy.
Int J Biol Macromol
October 2023
Biomaterials and Tissue Engineering Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781 039, India; Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati 781 039, India; Jyoti and Bhupat Mehta School of Health Sciences and Technology, Indian Institute of Technology Guwahati, Guwahati 781 039, India. Electronic address:
Intervertebral disc degeneration is a primary cause for chronic low back pain, a common health problem with high incidence and the leading cause of disability globally. The early stages of disc degeneration in terms of functional and anatomical abnormalities start from the central nucleus pulposus tissue of the intervertebral disc; hence its regeneration has become a prime concern. A plethora of hydrogel systems have been investigated as nucleus pulposus tissue substitute over the years, with limited clinical translation.
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