Enigmatic odyssey: A case of Behcet disease with atypical thrombotic complications.

Int J Surg Case Rep

Kaplan Heart Center, Kaplan Medical Center, Rehovot, Affiliated with the Hebrew University, Jerusalem, Israel; Harvard Medical School Postgraduate Medical Education, Global Clinical Scholer Research Training Program, Boston, USA; Head of Palestinian Clinical Research Center, Bethlehem, Palestine. Electronic address:

Published: November 2024

AI Article Synopsis

  • Behçet disease is a rare and chronic inflammatory condition that affects various organs and is mainly characterized by oral and genital ulcers, commonly diagnosed in young adults.
  • A case study of a 26-year-old woman highlights an unusual presentation of the disease, showcasing serious complications like recurrent thrombotic events, which are uncommon for her demographic.
  • The findings emphasize the importance of understanding Behçet disease's potential for serious complications and the need for prompt and tailored treatment strategies to improve patient outcomes.

Article Abstract

Introduction And Importance: Behçet disease is a rare, chronic, multi-systemic inflammatory disease of unknown origin that affects vessels in various organs. It is characterized by multiple clinical manifestations, most prominently oral and genital ulcers. Typically diagnosed in individuals aged 20 to 40 years with a male predominance, Behçet disease poses significant diagnostic and therapeutic challenges.

Case Presentation: We present a case concerning a 26-year-old female who was diagnosed with Behçet's disease nine years ago. This presentation is atypical for her age and gender. The patient has experienced recurrent thrombotic events, such as pulmonary embolism, a right pulmonary artery aneurysm, and right atrium intracardiac thrombosis.

Clinical Discussion: This case underscores the atypical presentation of Behçet disease in a young female and highlights its potential for serious thrombotic complications. The recurrent thrombotic events observed in this patient necessitate a comprehensive understanding of the disease's pathophysiology and tailored therapeutic approaches.

Conclusion: Behçet disease can manifest with significant thrombotic complications, even in atypical patient populations. This case report highlights the necessity for heightened awareness and timely management of thrombotic events in individuals with Behçet disease to enhance outcomes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11471680PMC
http://dx.doi.org/10.1016/j.ijscr.2024.110389DOI Listing

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