AI Article Synopsis
- T helper 2 (T2) cells play a key role in type 2 immunity, helping the body fight off parasitic infections and maintain tissue balance.
- When T2 cells act inappropriately against harmless substances, they can contribute to allergic conditions like asthma.
- New technologies are revealing important details about how T2 cells develop and function at a molecular level.
Article Abstract
T helper 2 (T2) cells orchestrate type 2 immunity during protective antihelminth immunity and help restore tissue homoeostasis. Their misdirected activities against innocuous substances also underlie atopic diseases, such as asthma and allergy. Recent technological advances are uncovering novel insights into the molecular mechanisms governing T2 cell differentiation and function.
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| http://dx.doi.org/10.1016/j.coi.2024.102483 | DOI Listing |
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