Introduction: Oral mucosal lesions though mostly benign, may impair the quality of life of patients. Some may even progress to malignancies. Many physicians, including dermatologists, tend to skip oral examinations, missing many important diagnoses. Understanding the frequency and types of oral mucosal lesions in dermatological settings can help in early diagnosis, referral and adequate treatment. This study was done to determine demographic characteristics and clinical presentations of patients with oral mucosal lesions presenting to the out-patient department (OPD) of dermatology in Nepal Armed Police Force (APF) Hospital, Kathmandu.
Methods: This cross-sectional descriptive study was conducted after obtaining the ethical approval from the Institutional Review Committee of Nepal APF Hospital. Retrospective data of 264 patients presenting with oral mucosal lesions to the dermatology OPD were collected from 1st January 2021 to 31st December 2023 by using a pre-formed proforma. Data was entered in SPSS software and descriptive statistics were computed.
Results: Out of 13,832 cases, oral mucosal lesion was seen in 264 (1.90%) cases among which 153 (57.96%) cases were males with male female ratio of 1.37:1. Most common age group affected was 31-45 years 96 (36.36%). Buccal mucosa 86 (32.57%) was the commonest site involved followed by tongue 73 (27.65%). Aphthous ulcer 82 (31.06%) was the commonest lesion found followed by oral candidiasis 25 (9.46%) and oral lichen planus 24 (9.09%).
Conclusions: Aphthous ulcer was the commonest oral mucosal lesion seen in patients visiting dermatology outpatient department of Nepal APF Hospital, with buccal mucosa being the commonest site affected.
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http://dx.doi.org/10.31729/jnma.8618 | DOI Listing |
Microbiol Immunol
December 2024
Department of Oral Microbiology and Immunology, Showa University Graduate School of Dentistry, Shinagawa-ku, Tokyo, Japan.
The oral microbiome is closely involved in the maintenance of host health and the development of systemic diseases. The salivary glands play an essential role in homeostasis in the oral cavity. Here, we investigated the effects of periodontal inflammation on salivary gland function and the oral microbiome.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
December 2024
Oral Technology, Dental School, University Hospital Bonn, Bonn, Germany. Electronic address:
Objective: To evaluate the biomechanical performance of various designs of cantilevered three-unit implant-supported prostheses, using two distinct prosthetic materials and under different loading conditions.
Method: Three mandibular models were created with varying implant positions to support a 3-unit prosthesis using two materials (Zirconia and PEKK), resulting in three different designs: distal cantilever (M1), fixed-fixed (M2), and mesial cantilever (M3). The geometric model was created by segmenting a CBCT scan of an edentulous mandible using Mimics software, followed by refinement in 3-Matic to generate a trabecular bone core encased by a 2 mm-thick cortical shell and a 1 mm-thick mucosal layer.
Cell Mol Biol (Noisy-le-grand)
November 2024
Water Resources Engineering Department, College of Engineering, University of Duhok, Kurdistan Region- Iraq.
Candida albicans is an opportunistic fungal pathogen. It's a dimorphic fungus with hyphal form that can penetrate and proliferate the oral mucosa. Occlusal guard materials come into direct contact with the oral mucosa and saliva when worn for extended periods, the occlusal guard acts as a reservoir for C.
View Article and Find Full Text PDFJ Dent Res
December 2024
Beijing Laboratory of Oral Health and Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
In addition to breaking down food, mastication plays regulatory roles in tissue homeostasis. During mastication, the oral mucosa is subjected to masticatory stress, and the maintenance between mucosal damage and repair is a key process. Despite rapid healing in the oral mucosa during chewing, the molecular mechanisms underlying repair remain unclear.
View Article and Find Full Text PDFMycopathologia
December 2024
Dermatology Hospital, Southern Medical University, Guangzhou, China.
We presented a case of chronic mucocutaneous candidiasis (CMC) due to STAT1 GOF mutation with recurrent enteritis and intestinal obstruction. A 33-year-old woman complained of recurrent oral erosion and finger (toe) nails damage for over 30 years. Candida albicans were cultured from the oral mucosa and nails.
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