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Prospective observational study on scar sequelae after MPOX infection: an analysis of 40 patients. | LitMetric

AI Article Synopsis

  • - Monkeypox (MPOX) recently experienced a resurgence, leading the WHO to declare a public health emergency, but there's limited knowledge on its long-term effects, especially scarring.
  • - A study focused on assessing scarring risk and characteristics in patients at a tertiary hospital, following up with 40 diagnosed individuals over 12-15 months after infection.
  • - Findings showed that nearly 48% of patients developed scars, impacting their quality of life, particularly in sensitive areas; the small sample size and follow-up issues could influence the reliability of these findings.

Article Abstract

Background: Monkeypox (MPOX) caused a public health emergency of international concern (PHEIC) outbreak between 2022 and 2023, with a recent rise in cases that prompted the World Health Organization (WHO) to declare the disease a PHEIC once again. There is little information on its long-term scarring sequelae.

Objectives: The objective of this study was to assess the risk and characteristics of scarring in patients with MPOX in a tertiary hospital.

Methods: This is a prospective cohort study including patients diagnosed using polymerase chain reaction (PCR) tests. Clinical data were collected and followed up at 12-15 months to assess scarring and its impact on quality of life.

Results: Of the 40 patients, 19 (47.5%) developed scars, which were more common in those with initial cutaneous manifestations. Scars significantly affected the quality of life, especially in the genital and mucosal areas. The limited sample and loss to follow-up may affect the validity of the results.

Conclusion: Scarring is a frequent and disfiguring sequela of MPOX, particularly in patients with early skin symptoms. Prevention and close follow-up are crucial in mitigating these complications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589025PMC
http://dx.doi.org/10.1111/ijd.17500DOI Listing

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