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Guyton's hemodynamic mosaic: crafting fluid management with precision.
Ann Intensive Care
January 2025
Intensive Care Department, Hospital Israelita Albert Einstein, Av. Albert Einstein, 627/701 - Morumbi, São Paulo, CEP: 05651-901, SP, Brasil.
Sheldon Magder's article on applying Arthur Guyton's principles to clinical fluid management provides valuable insights into optimizing hemodynamics in critically ill patients. While emphasizing the role of right atrial pressure (RAP) in assessing cardiac output, challenges arise due to RAP's variable accuracy and the oversimplification of cardiovascular dynamics. Integrating RAP with dynamic assessments and bedside ultrasound can enhance fluid management strategies.
View Article and Find Full Text PDFBackground: Subtle changes in naturalistic language have been associated with cognitive abilities in older adults. This study explored script generation as a method for detection of mild cognitive impairment (MCI). Differences in human-coded speech analysis of scripts were examined between MCI vs.
View Article and Find Full Text PDFCommentary on "Frailty as a predictor of mortality in the oldest old: A systematic review and meta-analysis".
Geriatr Gerontol Int
January 2025
Department of Paediatrics, Dr. D. Y. Patil Medical College Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University), Pune, India.
Commentary: Review of Mandatory Maintenance of Certification in the USA.
Eval Health Prof
January 2025
Jewish General Hospital, Canada.
The goal of maintenance of certification (MOC) activities is to ensure physicians are up to date on current practices and demonstrate the knowledge and skills required to provide patients with optimal care. The program's aim is to promote professional development, lifelong learning and quality assurance for the public and medical community. However, physicians are not happy with the current structure of the program, claiming it to be time-consuming, expensive and ineffective for their practice.
View Article and Find Full Text PDFPlatelets and monocytes: A dynamic duo aiding in the prediction of the clinical response to thrombopoietin receptor agonists in immune thrombocytopenia?
Br J Haematol
January 2025
Sanquin Research, Department of Experimental Immunohematology, Amsterdam and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Patients with immune thrombocytopenia (ITP) suffer from an autoimmune bleeding disorder with an isolated low number of platelets. Platelets and megakaryocytes are targeted by the immune system, due to a loss of immune tolerance, via the action of platelet-autoantibodies and/or cytotoxic T cells. ITP is a highly variable disorder regarding the underlying biological mechanisms, disease trajectories and treatment responses.
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