AI Article Synopsis
- Scientists have made new discoveries about Alzheimer’s disease (AD) and found two treatments called lecanemab and donanemab that work well!
- Researchers are excited about tiny medicines that can break down amyloid-beta (Aβ), which could improve how we treat AD!
- Even though there are some challenges, these new treatments might be the future solution for Alzheimer’s, thanks to recent scientific progress!
Article Abstract
Recent advancements in Alzheimer's disease (AD) research have led to the approval of lecanemab and donanemab, highlighting the effectiveness of amyloid-beta (Aβ) degradation as a treatment for AD. The prospect of small molecule Aβ degraders as a potential treatment, which utilizes emerging targeted protein degradation technology, is exciting, given their ability to address some of the limitations of current therapies and their promising future in AD treatment. Despite facing challenges, these degraders are poised to become a future treatment option, harnessing scientific breakthroughs for more targeted and effective AD therapy.
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| http://dx.doi.org/10.1021/acschemneuro.4c00590 | DOI Listing |
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