AI Article Synopsis
- After laparoscopic gallbladder surgery, some older patients experience confusion called postoperative delirium, which this study wanted to understand better.
- The researchers tested 84 patients over 60 years old to see how their Mini-Cog scores (a simple brain test) and two anesthesia methods (sevoflurane and TIVA) affected their chances of getting delirium.
- They found that patients with low Mini-Cog scores had a higher risk of confusion after surgery, and those who received sevoflurane were more likely to experience delirium compared to those who had TIVA.
Article Abstract
Background: Postoperative delirium is a common distressing symptom experienced following laparoscopic cholecystectomy. The study aimed to investigate the influence of a low preoperative Mini-Cog testing score and 2 different anesthesia methods: total intravenous anaesthesia (TIVA) versus sevoflurane, on postoperative delirium in elderly patients undergoing laparoscopic cholecystectomy.
Methods: A total of 84 patients over 60 years old who underwent laparoscopic cholecystectomy between March 1and - October 1 2023 were included in the study. Patients with a Mini-Cog score of 0-2 were considered to have low and possibly impaired neurocognitive function. We invastigated the effects of preoperative Mini-Cog score and the two anesthesia methods used on the incidence of postoperative delirium.
Results: The proportion of patients with low Mini-Cog score in the preoperative period was 17.9%. Sevoflurane and TIVA was used in 41 and 43 patients respectively. The incidence of postoperative delirium in patients with low preoperative Mini-Cog scores was 66.7% at postoperative 0 h and 33.3% at the 1st hours. Postoperative delirium was found to be statistically higher in patients with low Mini-cog scores than in those with negatively-screened for Mini-cog scores (p: 0.01-0.035). In patients using sevoflurane, the incidence of postoperative delirium was 26.8% and 24.4% at the 0 and 1st hours, respectively. This was found to be statistically higher than in patients receiving TIVA (p: 0.036 - 0.010).
Conclusion: Low Mini-Cog score was an indicator of a higher risk of early postoperative delirium. Sevoflurane is more likely to cause postoperative delirium than TIVA.
Trial Registration: The study was registered on ClinicalTrials.gov (Identifier: NCT06597812) .
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443701 | PMC |
| http://dx.doi.org/10.1186/s12871-024-02735-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Determining influences of intraoperative s-ketamine on postoperative delirium and cognitive function: methodology is important.
J Cardiothorac Surg
December 2024
Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No. 134 Dongjie, Fuzhou, 350001, China.
The letter to the editor was written in response to the recent article by Wang et al. "The influence of low-dose s-ketamine on postoperative delirium and cognitive function in older adults undergoing thoracic surgery", which is published in Journal of Cardiothoracic Surgery. 2024; 19(1):324.
View Article and Find Full Text PDFEffects of glucocorticoids on postoperative delirium in patients undergoing elective non-cardiac surgery:A systematic review and meta-analysis.
Heliyon
December 2024
Department of Anesthesiology, Dalian Municipal Central Hospital, Dalian Medical University, Dalian, 116033, Liaoning, China.
Background: Postoperative delirium (POD) is common postoperative complications in non-cardiac surgery. While delirium prophylaxis has not yielded unequivocal support. The clinical effects of glucocorticoids on POD remains unclear.
View Article and Find Full Text PDFA Case of Acute Aortic Dissection in an Older Patient of Advanced Age.
Cureus
November 2024
Cardiovascular Surgery, Sapporo Medical University, Sapporo, JPN.
The patient an 85-year-old female resided in a care facility where she maintained an independent daily activity level. She was discovered hunched over a table in her room, displaying reduced responsiveness and prompting an emergency call. Initially, her blood pressure was within 60 mmHg, and she was transported by ambulance to our hospital.
View Article and Find Full Text PDFThe effect of toluene sulfonic acid remimazolam on postoperative delirium in elderly patients undergoing painless bronchoscopy.
Sci Rep
December 2024
Department of Anesthesia and Perioperative Medicine, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, China.
Toluene sulfonic acid remimazolam is a novel benzodiazepine that differs from traditional benzodiazepines (BZDs) due to its rapid onset, swift metabolism, and lack of hepatic or renal metabolism, as well as its reduced effects on cardiac and cerebral functions. Despite its potential advantages, clinical experience with this agent remains limited. This study investigated the effect of remizolam on postoperative delirium in elderly patients undergoing painless bronchoscopy.
View Article and Find Full Text PDFEfficacy of Repetitive Transcranial Magnetic Stimulation in Preventing Postoperative Delirium in Elderly Patients Undergoing Major Abdominal Surgery: A Randomized Controlled Trial.
Brain Stimul
December 2024
Department of Anesthesiology, The Affiliated Hospital of Nantong University, Nantong, 226001, China. Electronic address:
Background: Postoperative delirium (POD) is a serious complication in elderly patients after major surgery, associated with high morbidity and mortality. Treatment and prevention methods are limited. Repetitive transcranial magnetic stimulation (rTMS) shows potential in enhancing cognitive function and improving consciousness.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!