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Salt-and-pepper skin pigmentation.
Cleve Clin J Med
October 2024
Professor and Head, Department of Dermatology, Venereology, and Leprosy, Aarupadai Veedu Medical College and Hospital, Puducherry, India
Pigmentary Changes in Systemic Sclerosis are Associated with More Severe Cutaneous Sclerosis and Severity of Other Systems: A Cross-sectional Study from India.
Indian J Dermatol
August 2024
Department of Biostatistics, AIIMS, New Delhi, India.
Article Synopsis
- The study investigates the relationship between skin pigmentation changes in systemic sclerosis and the severity of cutaneous sclerosis as well as internal organ involvement.
- It found that patients with pigmentary alterations had significantly higher modified Rodnan skin scores, indicating more severe skin involvement.
- While most patients had lung complications, those with skin pigmentation exhibited lower scores on high-resolution CT scans, suggesting a complex interaction between skin changes and organ health.
Clinical outcomes and associated factors with mortality in systemic sclerosis patients with sarcopenia.
Am J Med Sci
July 2024
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address:
Background: Despite the high incidence of sarcopenia in systemic sclerosis (SSc) patients, there is currently limited evidence on their outcomes.
Objectives: Our study aimed to determine clinical courses, outcomes, and identify factors associated with mortality in the SSc patients with sarcopenia.
Methods: A historical cohort study was conducted in 180 adult SSc patients diagnosed with sarcopenia according to the criteria of Asian Working Group for Sarcopenia 2019, who were attending the Scleroderma Clinic at Khon Kaen University between July 2019 and November 2021.
Clinical courses and predictors of left ventricular systolic dysfunction in systemic sclerosis: A cohort study.
Rheumatol Immunol Res
June 2024
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Background And Objectives: Left ventricular systolic dysfunction (LVSD) is a cardiac involvement that is the leading cause of death among patients with systemic sclerosis (SSc). We aimed to define the clinical course and predictors of LVSD among SSc patients.
Methods: We conducted a cohort study among adult patients with SSc who were followed up from 2013 to 2020.
An unusual duo: Immunodeficiency disorder and scleroderma.
Indian J Sex Transm Dis AIDS
June 2024
Department of Rheumatology Institute of Rheumatology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai, Tamil Nadu, India.
A 45-year-old woman on treatment for HIV infection with highly active antiretroviral therapy for the past 10 years presented to us with a history of Raynaud's phenomenon and hyperpigmentation of the skin for 2 years. She was diagnosed to have pulmonary arterial hypertension 8 months ago. On examination, she had salt-and-pepper pigmentation and sclerodactyly.
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