Purpose: Since 2014, an educational activity on radiation and health in northern Japan has been carried out by young scientists, the so-called 'Educational Symposium on Radiation and Health (ESRAH)'. Close cooperation has been continued in preparing for any possible emergency response to radiation accidents because several facilities, e.g., the Tomari Nuclear Power Plant in Hokkaido and the Low-Level Radioactive Waste Disposal Facility in Aomori prefecture. The ESRAH meeting has provided informational exchange and discussion forum on a broad range of subjects in various. In 2023, the 10th Memorial ESRAH meeting took place to boost scientific understanding and multidisciplinary collaborations for young scientists. Herein, we report on the ESRAH2023 symposium and analyze the research categories of young scientists from the past 10-year presentations.
Conclusions: To date, the ESRAH meeting has successfully provided a chance for multi-disciplinary research, which accounted for 27% of the total despite the COVID-19 pandemic. We found that the fraction of multi-disciplinary research in 2023 was the highest during 10-year ESRAH meetings. Meanwhile, amongst the research categories, physics, chemistry, and pharmacological studies were indicated to be less for young scientists. It is desired that further collaboration between physics, chemistry, and pharmacology in addition to the current fields would not only clarify radiation effects on the human body but also promote emergency medical care for radiation exposure in the future.
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http://dx.doi.org/10.1080/09553002.2024.2409671 | DOI Listing |
Int J Cancer
January 2025
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Early Drug Development Center, Peking University Cancer Hospital and Institute, Beijing, China.
Pancreatic cancer is a particularly aggressive tumor, distinguished by the presence of a prominent collagenous stroma and desmoplasia that envelops the tumor cells. Pancreatic stellate cell (PSC) contributes to the formation of a dense fibrotic stroma and has been demonstrated to facilitate tumor progression. As the significance of PSCs is increasingly revealed, more explorations are focused on the complex molecular mechanisms and tumor-stromal crosstalk in order to guide potential therapeutic approaches through deactivating or reprogramming PSCs.
View Article and Find Full Text PDFMol Cancer
January 2025
Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
The study of the multifaceted interactions between neuroscience and cancer is an emerging field with significant implications for understanding tumor biology and the innovation in therapeutic approaches. Increasing evidence suggests that neurological functions are connected with tumorigenesis. In particular, the peripheral and central nervous systems, synapse, neurotransmitters, and neurotrophins affect tumor progression and metastasis through various regulatory approaches and the tumor immune microenvironment.
View Article and Find Full Text PDFSci Rep
January 2025
Research Center for Pre-Disease Science, Faculty of Education and Research Promotion, University of Toyama, Toyama, 930-0194, Japan.
Adipose tissue (AT) metabolism involves coordinating various cells and cellular processes to regulate energy storage, release, and overall metabolic homeostasis. Therein, macrophage and its cytokine are important in controlling tissue homeostasis. Among cytokines, the role of transforming growth factor-β1 (Tgf-β1), a cytokine abundantly expressed in CD206 M2-like macrophage and correlated with the expansion of AT and fibrosis, in AT metabolism, remains unknown.
View Article and Find Full Text PDFBrain Stimul
January 2025
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.
Eur J Radiol
January 2025
Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China; Department of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China; Department of Pulmonary and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address:
Purpose: This head-to-head comparative meta-analysis aimed to evaluate the comparative diagnostic efficacy of [F]FDG PET/CT and dynamic contrast-enhanced CT(DCE-CT) for the differentiation between malignant and benign pulmonary nodules.
Methods: An extensive search was conducted in the PubMed, Embase, and Web of Science to identify available publications up to March 23, 2024. Studies were included if they evaluated the diagnostic efficacy of [F]FDG PET/CT and DCE-CT for the characterization of pulmonary nodules.
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