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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11440346 | PMC |
| http://dx.doi.org/10.1016/j.opresp.2024.100361 | DOI Listing |
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[Ulcers and diabetic foot : Modern and alternative treatment strategies].
Dermatologie (Heidelb)
December 2024
Colentina Klinik, Dermatologie 2, "Carol Davila" Universität für Medizin und Pharmazie, Bukarest, Rumänien.
Treatment of diabetic foot is challenging due to the complex pathophysiological mechanisms, various clinical manifestations, severe complications with considerable impairment of quality of life, and the need for special, individualized treatment strategies. Particularly in the case of diabetic foot ulcers, conventional therapies are not always effective, so new treatment strategies are needed. This review aims to present alternative therapies with current efficacy data for diabetic foot ulcers that may be suitable for treatment-refractory ulcers.
View Article and Find Full Text PDFUpdate Motility Disorders: Gastro-Oesophageal Reflux Disease - Diagnostic and Conservative Approach.
Visc Med
December 2024
Digestive Function: Basel, Laboratory and Clinic for Motility Disorders and Functional Digestive Diseases, Centre for Integrative Gastroenterology, Klinik Arlesheim, Arlesheim, Switzerland.
Background: Gastro-oesophageal reflux disease (GORD) is extremely common, with at least 1 in 10 people in the general population reporting heartburn and acid regurgitation on a weekly basis. GORD can also be associated with a variety of atypical symptoms, including chest pain, chronic cough, and laryngopharyngeal symptoms. The causes of GORD are multifactorial, and the severity of symptoms is influenced by peripheral and central factors, including psychosocial stress and anxiety.
View Article and Find Full Text PDFPatients with refractory musculoskeletal pain syndromes undergoing a multimodal assessment and therapy programme: a cross-sectional study.
Swiss Med Wkly
October 2024
Department of Rheumatology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Background: Chronic musculoskeletal pain syndromes, including fibromyalgia, are heterogeneous entities with a major socioeconomic burden. Multimodal treatment programmes have shown greater efficacy than conventional approaches for these patients, at least in the short term. A profound understanding of chronic musculoskeletal pain syndrome patients treated in multimodal treatment programmes is important for their development and to provide insight into these conditions.
View Article and Find Full Text PDFLong-term clinical course of complex pulmonary disease patients with treatment failure.
Antimicrob Agents Chemother
December 2024
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Article Synopsis
- Some patients with complex pulmonary disease (MAC-PD) still experience treatment failure despite following guidelines; an analysis of 271 patients showed that 51% needed retreatment after stopping therapy.
- Patients were divided into retreatment and stable groups, with several factors like elevated erythrocyte sedimentation rates, presence of lung cavities, and extent of bronchiectasis linked to the need for retreatment.
- This study highlights that about half of the patients who stopped antibiotics may eventually require them again, suggesting that the severity of lung damage influences treatment decisions.
Chronic active Epstein-Barr Virus infection in a teenage girl with suspect autoimmune Hepatitis.
BMC Pediatr
October 2024
Division of Pediatric Gastroenterology, Department of Pediatrics, Linkou Branch, Chang Gung Children's Medical Center, Chang Gung Memorial Hospital, No. 5, Fuxing St., Guishan Dist, Taoyuan City, 33305, Taiwan.
Article Synopsis
- Chronic active Epstein-Barr virus (CAEBV) disease can mimic autoimmune hepatitis (AIH) due to similar symptoms and liver enzyme elevations, complicating diagnosis.
- A case is presented of a 14-year-old girl misdiagnosed with AIH who was later found to have CAEBV after testing positive for EBV markers and DNA, leading to diverse treatment options that were ultimately refused by her family.
- The study highlights the importance of considering CAEBV in patients with AIH-like symptoms, especially when they do not respond to standard treatment methods.
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