() is a Gram-negative anaerobic bacterium that plays a key role in the development of oral inflammation, such as periodontitis and gingivitis. In the last 10 years, has been identified as a prevalent bacterium associated with colorectal adenocarcinoma and has also been linked to cancer progression, metastasis and poor disease outcome. While the role of in colon carcinogenesis has been intensively studied, its role in gastric carcinogenesis is still poorly understood. Although infection has historically been recognized as the strongest risk factor for the development of gastric cancer (GC), with recent advances in DNA sequencing technology, other members of the gastric microbial community, and in particular, have received increasing attention. In this review, we summarize the existing knowledge on the involvement of in gastric carcinogenesis and address the potential translational and clinical significance of in GC.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11438658 | PMC |
http://dx.doi.org/10.3748/wjg.v30.i35.3972 | DOI Listing |
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