AI Article Synopsis
- - Rheumatoid arthritis (RA) is an autoimmune disease that weakens the immune system, making patients more vulnerable to infections, especially when treated with immunosuppressive medications.
- - A case study reports a Caucasian patient in South-eastern Europe who developed prolonged eosinophilia while being treated with upadacitinib for RA, eventually diagnosed with Strongyloidiasis despite living in a non-endemic area.
- - The study highlights the need for regular medical follow-ups for immunocompromised patients and the importance of being aware of both common and uncommon infections that can arise during their treatment.
Article Abstract
Rheumatoid arthritis (RA) is a systemic disease, which is caused by dysregulation of the immune system in the 'susceptible' persons, making them immunocompromised and prone to infections during the course of their disease. The majority of RA patients are being treated with immunosuppressive drugs which render them even more immunocompromised. We present a Caucasian patient living in South-eastern Europe who developed prolonged eosinophilia during the treatment of RA with upadacitinib. After a comprehensive work-up, she was diagnosed with strongyloidiasis, although she was living in non-endemic region of the world. We emphasise the importance of regular follow-up for immunocompromised patients and raise awareness of not only typical but also atypical infections that can occur during the course of the disease.
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| http://dx.doi.org/10.1093/mrcr/rxae061 | DOI Listing |
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