AI Article Synopsis
- Invasive migration of cells involves overcoming extracellular matrix barriers, a process that requires significant energy.
- Park et al. emphasize the role of synthesizing fatty acids, phospholipids, and isoprenoids in facilitating the invasive movement of the Caenorhabditis elegans anchor cell.
- This research underscores how essential these biosynthetic pathways are for developmental processes that require cells to migrate through tough membranes.
Article Abstract
Invasive migration requires cells to break through extracellular matrix barriers, which is an energy-expensive process. In this issue, Park et al. (https://doi.org/10.1083/jcb.202402035) highlight the importance of biosynthesis of fatty acids, phospholipids, and isoprenoids in driving invasive migration of the Caenorhabditis elegans anchor cell through a basement membrane barrier during development.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441311 | PMC |
| http://dx.doi.org/10.1083/jcb.202408005 | DOI Listing |
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