An Atypical Presentation of a Patient With Neurosarcoidosis: A Case Report.

Cureus

Internal Medicine, Rochester Regional Health, Rochester, USA.

Published: August 2024

AI Article Synopsis

  • - Neurosarcoidosis is a condition where noncaseating granulomas, typical of sarcoidosis, are present in the nervous system, affecting areas like the brain and spinal cord.
  • - The case report discusses a 57-year-old man experiencing progressive weakness and numbness in his legs, as well as eye issues, which led to further testing.
  • - Imaging revealed lymph node enlargement, and biopsies confirmed the presence of granulomas, suggesting neurosarcoidosis; thus, doctors should consider this diagnosis when patients exhibit similar symptoms for timely treatment.

Article Abstract

Neurosarcoidosis is a disease in which noncaseating granulomas, characteristic of sarcoidosis, are found within organs of the nervous system such as the brain and spinal cord. This case report highlights a 57-year-old male with worsening bilateral lower extremity weakness and numbness in addition to ptosis and oculomotor nerve palsy of the right eye. Computed tomography (CT) imaging showed mediastinal and hilar lymphadenopathy, which raised suspicion for neurosarcoidosis. Multiple biopsies were taken from lymph nodes in the mediastinal region, which resulted in non-necrotizing epithelioid cell granulomas, consistent with the suspected neurosarcoidosis. Medical providers must include neurosarcoidosis within a much broader differential diagnosis when encountering patients that present with a similar presentation shown in this case report so that treatment can be promptly initiated as soon as possible.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439466PMC
http://dx.doi.org/10.7759/cureus.68229DOI Listing

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