Background: In order to completely remove bacteria and debris from the root canal system, root canal treatment (RCT) calls for efficient irrigation methods. There is still a lack of research on the relative safety and efficacy of various irrigation systems in tertiary care settings.
Methods: Patients receiving RCT at a tertiary care endodontic clinic were included in a prospective comparison research of 150 subjects. One of four irrigation solutions-sodium hypochlorite, chlorhexidine, ethylenediaminetetraacetic acid (EDTA), or a combination of the three-was given to patients at random. Following surgery, microbial decrease and patient-reported pain levels were evaluated.
Results: The analysis showed that there were significant differences ( < 0.05) in microbial decrease between the irrigation solution groups. EDTA, sodium hypochlorite, and chlorhexidine were the next three groups with the biggest mean log decrease in microbial counts, after the combination group. Nonetheless, there were no appreciable variations in the groups' patient-reported pain levels ( > 0.05).
Conclusion: Our results imply that microbial reduction in RCT is highly influenced by the irrigation solution selection. Without having an impact on the pain sensations reported by the patients, the combination of irrigation solutions showed higher efficacy in microbial control. These findings highlight how crucial it is to choose an irrigation solution carefully in order to maximize endodontic outcomes in tertiary care settings.
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http://dx.doi.org/10.4103/jpbs.jpbs_277_24 | DOI Listing |
Braz J Otorhinolaryngol
January 2025
Shanghai Jiao Tong University, School of Medicine, Hainan Branch of Shanghai Children's Medical Center, Department of Otorhinolaryngology, Sanya, China; Shanghai Jiao Tong University, School of Medicine, Shanghai Children's Medical Center, Department of Otorhinolaryngology, Shanghai, China. Electronic address:
Objective: We aimed to investigate the correlation between prevalent risk factors for high-risk neonates in neonatal intensive care unit and their hearing loss, and to examine the audiological features and genetic profiles associated with different deafness mutations in our tertiary referral center. This research seeks to deepen our understanding of the etiology behind congenital hearing loss.
Methods: We conducted initial hearing screenings, including automated auditory brainstem response, distortion product otoacoustic emission, and acoustic immittance on 443 high-risk neonates within 7 days after birth and 42 days (if necessary) after birth.
Ann Med
December 2025
School of Public Health, Fudan University, Shanghai, China.
Background: Evaluation of health system responsiveness (HSR) can improve patient satisfaction, promote health equity and enhance the quality of health services.
Objectives: To explore the differences in HSR among medical institutions at different levels and in various domains.
Methods: A multi-stage stratified sampling method was used to select 820 participants aged 18 years and older from Kunshan City, China.
Indian Pediatr
January 2025
Community and Family Medicine, All India Institute of Medical Sciences, Deoghar, Jharkhand, India.
Objective: To estimate the proportion of eosinophilic and non-eosinophilic (NEA) endotypes in pediatric asthma, and to compare the clinical, and laboratory characterisitics, and different comorbidities between the two endotypes in the children.
Methods: Children aged 5 to 14 years of age with clinical and/or laboratory-confirmed asthma attending the pediatric outpatient department of a tertiary care hospital in Eastern India between October 1, 2023 and March 31, 2024, were included in this cross-sectional study. Complete hemogram, absolute eosinophil count (AEC), IgE, and pulmonary function tests were performed in all patients.
Indian Pediatr
January 2025
Department of Neonatology, St John's Medical College Hospital, Bangalore, Karnataka, India.
Introduction: Neonatal intensive care unit (NICU) graduates are at risk of sudden death at home after discharge. Many of these deaths can be prevented if parents can identify warning signs and provide immediate resuscitation.
Objectives: The primary objective of this study was to assess the feasibility of training parents of high-risk neonates in low- and middle-income countries (LMICs) to deliver infant resuscitation effectively.
Reprod Health
January 2025
Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Background: Over one-third of the global stillbirth burden occurs in countries affected by conflict or a humanitarian crisis, including Afghanistan. Stillbirth rates in Afghanistan remained high in 2021 at over 26 per 1000 births. Stillbirths have devastating physical, psycho-social and economic impacts on women, families and healthcare providers.
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