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Body temperature is a crucial indicator in assessing human physiological activity and health, particularly in pediatric and critically ill patients. This study aimed to compare temperature recordings obtained from digital calibrated thermometers with calibrated infrared thermometers and non-calibrated infrared thermometers against calibrated ones. An observational prospective study was conducted at AIIMS Bhopal, involving volunteers and febrile patients who consented to participate. Approval was obtained from the Institutional Human Ethics Committee, and 200 participants meeting inclusion/exclusion criteria were included. Data were collected and analyzed using Microsoft Excel. Mean and variance values were computed for both volunteer and febrile patient groups. The values in both groups were less than 0.05, indicating a significant difference between non-calibrated handheld infrared thermometers (T1), calibrated digital thermometers (T2), and their individual comparison with calibrated infrared thermometers (T3). Variance was higher in non-calibrated infrared thermometers (T1) compared to calibrated ones (T2) in both healthy volunteers and febrile patients. Pearson's correlation coefficient analysis within the febrile patient group demonstrated a robust positive correlation among all three thermometers compared to the healthy volunteers group. The study highlights variations in temperature readings when using different thermometers, irrespective of whether the assessment is conducted on healthy volunteers or febrile patients. Notably, the strength of association is lower in healthy volunteers than in febrile patients, suggesting that the interchangeability of thermometers may be more reliable and sufficient when assessing individuals with fever. These findings underscore the importance of careful consideration and validation of thermometer choices, especially in clinical settings where accurate temperature measurement is critical.
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http://dx.doi.org/10.4103/jpbs.jpbs_73_24 | DOI Listing |
Talanta
December 2024
Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, 5290002, Ramat Gan, Israel.
The dried matrix spot (DMS) method, initially developed for neonatal blood screening, has gained prevalence in various research fields for its efficiency in handling small sample volumes and its adaptability to diverse analytical techniques. This study presents the results of the first systematic investigation of direct multi-element analysis in DMS of human blood and plasma samples with Particle Induced X-ray Emission (PIXE). Internal standard addition was used to address the issue of DMS heterogeneity and to eliminate the need for determining the sample volume equivalent, allowing a single-spot (single-punch) measurement.
View Article and Find Full Text PDFIran J Immunol
December 2024
Department of General Surgery, Istanbul Training and Research Hospital, Istanbul, Turkey.
Background: Breast cancer is the leading cause of cancer-related deaths in women. Cytokines have been linked to various cancers, and both benign and malignant breast diseases are associated with inflammation. However, there is limited understanding of how the immune system's cytokine response varies among different subtypes of breast cancer.
View Article and Find Full Text PDFJ Ultrason
December 2024
Motion Analysis Laboratory, Institute of Physiotherapy and Health Sciences, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Aim: There is a need to evaluate the tissue deformation index of lateral abdominal muscles using M-mode ultrasound in a cohort of healthy subjects to establish a convenient reference point for clinical reasoning in patients. The aim of the study was to assess differences in the tissue deformation index between individual lateral abdominal muscles regardless of body side, compare these differences in the tissue deformation index on the right and left sides of the body, and evaluate side-to-side differences in the tissue deformation index within individual lateral abdominal muscles.
Material And Methods: In a group of 126 healthy volunteers (59 females), the postural response of lateral abdominal muscles to external perturbation in the form of rapid arm abduction with load was recorded on both sides of the body, and the tissue deformation index was calculated.
J Pain Res
December 2024
College of Acupuncture and Massage (Rehabilitation Medical College), Anhui University of Chinese Medicine, Hefei, People's Republic of China.
Purpose: The aim of the research was to observe the variations in brain activity between young cervical spondylosis patients with chronic neck pain (CNP) and healthy volunteers in the resting state and to investigate the central remodeling mechanisms in the patients.
Patients And Methods: Our study recruited 31 patients with chronic neck pain from cervical spondylosis and 30 healthy volunteers. Eventually, 29 patients (CNP group) and 29 healthy volunteers (HC group) completed the acquisition of clinical data and resting-state functional magnetic resonance ( BOLD-fMRI) amplitude of low-frequency fluctuations (ALFF) data; in addition, we assessed the relationship between differentially active brain regions and clinical indicators.
J Endocr Soc
November 2024
VA Northwest Mental Illness Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108, USA.
Context: Many studies have moved toward saliva and peripheral blood sampling for studying cortisol, even in relation to disorders of the brain. However, the degree to which peripheral cortisol reflects central cortisol levels has yet to be comprehensively described. Data describing the effect that biological characteristics such as age and sex have on cortisol levels across compartments is also limited.
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