AI Article Synopsis
- * Dental and eye examinations were conducted by specialists to identify periodontal disease and specific types of AMD in 200 participants, using standardized criteria.
- * Findings revealed that factors like age, education level, income, hypertension, cardiovascular disease, and hepatitis B are significantly associated with AMD, particularly in individuals under 60.
Article Abstract
Background And Aim: Periodontal disease may result in chronic inflammation and bacteremia in some people. The study aimed to evaluate the connection between periodontal disease and macular degeneration.
Materials And Methods: The specialist dental surgeon conducted the dental examination using a community periodontal index probe. An ophthalmologist performed the eye examination. Age-related macular degeneration (AMD) was identified through specific criteria such as the existence of particular types of drusen and pigmentary abnormalities.
Results: Two hundred participants were part of the study. According to the data, factors such as advanced age, limited education, low income, hypertension, cardiovascular disease (CVD), and hepatitis B surface antigen (HBsAg) presence were strongly linked to AMD in all participants.
Conclusion: Multiple studies have indicated a connection between periodontitis in the mouth and macular degeneration in individuals under 60 years of age.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426889 | PMC |
| http://dx.doi.org/10.4103/jpbs.jpbs_175_24 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Kotter's change management approach to transforming oral healthcare delivery: A case study.
J Dent Educ
January 2025
Department of Diagnostic and Biomedical Sciences, UTHealth Houston School of Dentistry, Houston, Texas, USA.
Introduction: Despite progress in research and technological advancements, the delivery of oral health care continues to be plagued by disparities in accessibility and affordability. Dental caries and periodontal disease remain major issues, and new challenges such as socioeconomic disparities and emerging public health dangers also contribute to the complexity of the issue. To address these challenges, dental education and oral healthcare delivery must shift their focus from disease treatment to disease prevention and health promotion.
View Article and Find Full Text PDFDasatinib and Quercetin Limit Gingival Senescence, Inflammation, and Bone Loss.
J Dent Res
January 2025
Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Cellular senescence has emerged as one of the central hallmarks of aging and drivers of chronic comorbidities, including periodontal diseases. Senescence can also occur in younger tissues and instigate metabolic alterations and dysfunction, culminating in accelerated aging and pathological consequences. Senotherapeutics, such as the combination of dasatinib and quercetin (DQ), are being increasingly used to improve the clinical outcomes of chronic disorders and promote a healthy life span through the reduction of senescent cell burden and senescence-associated secretory phenotype (SASP).
View Article and Find Full Text PDFEffects of Combined Periodontal, Endodontic, and Dentoalveolar Surgical Treatments on Laboratory Parameters in Patients with Hyperlipidemia-A Clinical Interventional Study.
J Clin Med
January 2025
Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98, 4032 Debrecen, Hungary.
Patients with hyperlipidemia are of interest because of the possible interplay between chronic local dental infections and hyperlipidemia. This interventional clinical study aimed to evaluate the oral health status of hyperlipidemic patients receiving lipid-lowering therapy for at least 6 months and the effects of non-surgical and surgical dental treatments on serum C-reactive protein (CRP) levels and lipid markers. Twenty-eight patients with controlled hyperlipidemia and 18 healthy controls were enrolled in the study.
View Article and Find Full Text PDFThe Association Between Periodontal Inflamed Surface Area (PISA), Inflammatory Biomarkers, and Mitochondrial DNA Copy Number.
J Clin Med
December 2024
Department of Oral Medicine and Periodontology, Faculty of Medicine, University of Ljubljana, Hrvatski trg 6, 1000 Ljubljana, Slovenia.
: Periodontitis is an inflammatory disease induced by bacteria in dental plaque that can activate the host's immune-inflammatory response and invade the bloodstream. We hypothesized that a higher periodontal inflamed surface area (PISA) is associated with higher levels of inflammatory biomarkers, lower levels of antioxidants, and mitochondrial DNA copy number (mtDNAcn). : Using periodontal parameters, we calculated the PISA score, measured the levels of inflammatory biomarkers and antioxidants in the serum, and took buccal swabs for mtDNA and nuclear DNA (nDNA) extraction.
View Article and Find Full Text PDFRelationship Between Rheumatoid Arthritis and Periodontal Disease-Systematic Review and Meta-Analysis.
J Clin Med
December 2024
Faculty of Dentistry, Alfonso X El Sabio University, 28691 Madrid, Spain.
The aim of this systematic review and meta-analysis was to determine the association between rheumatoid arthritis and periodontal disease. This systematic review and meta-analysis of the scientific literature was carried out based on the recommendations of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We analyzed all studies that evaluated the relationship between the chronic inflammatory diseases through the response to non-surgical periodontal treatment, comparing the values of CAL (Clinical Attachment Level) for PD (periodontal disease) and DAS28 for RA.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!