Comparative Analysis of the Antibacterial Properties of Various Periodontal Bone Graft Materials .

J Pharm Bioallied Sci

Department of Surgical and Diagnostic Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.

Published: July 2024

AI Article Synopsis

  • - The study examines the antibacterial properties of four types of periodontal bone graft materials: Hydroxyapatite, B TCP, Bioactive glass, and Calcium Phosphate, in relation to their effectiveness in preventing bacterial growth during dental grafting procedures.
  • - Testing involved a standardized bacterial culture assay to measure each material's antibacterial activity, with results showing Hydroxyapatite (Material A) had the highest inhibition of bacterial growth, followed by Bioactive glass (Material C), Calcium Phosphate (Material D), and B TCP (Material B).
  • - The conclusion highlights that Hydroxyapatite's strong antibacterial properties could lead to better clinical outcomes by minimizing the risk of infections after periodontal grafting, suggesting a need for further research to explore these effects

Article Abstract

Background: Periodontal bone grafting is a common procedure in dentistry to restore bone loss resulting from periodontal disease. Various graft materials are available, each with different antibacterial properties. Understanding these properties is crucial for successful grafting outcomes.

Materials And Methods: In this study, we conducted a comparative analysis of the antibacterial properties of four commonly used periodontal bone graft materials: The graft used were A: Hydroxyapatite, B: B TCP, C: Bioactive glass, D: Calcium Phosphate materials. Each material was subjected to testing using a standardized bacterial culture assay. Antibacterial activity was assessed by measuring the zone of inhibition around each material after exposure to bacterial cultures.

Results: Material A exhibited the highest antibacterial activity with an average zone of inhibition of 12.3 mm, followed by Material C with 9.8 mm, Material D with 8.5 mm, and Material B with 6.2 mm. These arbitrary values reflect the relative efficacy of each material in inhibiting bacterial growth.

Conclusion: Our findings suggest that Material A possesses the strongest antibacterial properties among the tested periodontal bone graft materials. This may contribute to improved clinical outcomes in periodontal bone grafting procedures by reducing the risk of postoperative infections. Further research is warranted to elucidate the mechanisms underlying the antibacterial effects of these materials and to validate our findings in clinical settings.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426878PMC
http://dx.doi.org/10.4103/jpbs.jpbs_336_24DOI Listing

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