Retrospective Review of Treatment Outcomes in Epilepsy Patients: Seizure Control and Medication Side Effects.

J Pharm Bioallied Sci

Consultant and MD, Oral and MaxilloFacial Surgeon, Dr Pritee's Polyclinic, Navi Mumbai, Maharashtra, India.

Published: July 2024

AI Article Synopsis

  • This study analyzes treatment outcomes for epilepsy patients between 2017 and 2022, focusing on seizure control and medication side effects.
  • Out of 200 patients, 60% achieved complete seizure independence, while 30% had reduced seizure frequency; only 10% did not see improvement.
  • Different antiepileptic medications resulted in varying side effects, with older patients experiencing more fatigue than younger patients, highlighting the importance of customized treatment approaches.

Article Abstract

Background: Epilepsy management requires balancing seizure control with minimizing medication side effects. This retrospective review examines treatment outcomes in epilepsy patients, focusing on seizure control and medication-related adverse effects.

Methods: Medical records of epilepsy subjects treated tertiary care center between 2017 and 2022 were retrospectively reviewed. Data on demographic characteristics, seizure control, medication regimen, and side effects were collected and analyzed.

Results: A total of 200 subjects were included. Sixty percent of subjects achieved total seizure independence, 30% reduced seizure frequency, and 10% did not improve or deteriorate. The kind of antiepileptic medicine provided substantially affects prescription side effects ( < 0.05), with drug X causing more dizziness than drug Y ( = 0.02). Elderly individuals were more likely to suffer weariness than younger ones ( = 0.03).

Conclusion: This review provides valuable insights into epilepsy treatment outcomes, emphasizing the need for personalized management strategies to optimize seizure control while minimizing medication-related adverse effects.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426786PMC
http://dx.doi.org/10.4103/jpbs.jpbs_246_24DOI Listing

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