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Unveiling the Hidden Dangers: Massive Allergic Dermatitis After Hyaluronic Acid Injection. | LitMetric

Unveiling the Hidden Dangers: Massive Allergic Dermatitis After Hyaluronic Acid Injection.

Clin Cosmet Investig Dermatol

Department of Cosmetic Injection Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100144, People's Republic of China.

Published: September 2024

AI Article Synopsis

  • The increasing popularity of hyaluronic acid (HA) implants has led to more noticeable side effects, including a rare case of severe allergic dermatitis from HA injections.
  • Through dermoscopy and color ultrasound, the study confirmed that the dermatitis was indeed caused by the fillers and explored possible allergy triggers.
  • The patient was effectively treated with a low dose of 5-fluorouracil and triamcinolone acetonide, and the findings aim to enhance understanding of HA-related skin reactions and encourage further research on their underlying causes.

Article Abstract

The increasing use of hyaluronic acid (HA) implants has made adverse effects more apparent. Here, we present a rare case of massive allergic dermatitis due to HA injections. We performed dermoscopy and color ultrasound, which clarified that this was an allergic dermatitis caused by fillers, and analyzed the possible causes of the allergy. Common treatments were compared, and the advantages of 5-FU-based treatment regimens and their associated mechanisms were noted. A low dose of 5-fluorouracil and triamcinolone acetonide was administered to the patient's entire face and neck, and significant efficacy was achieved. We aimed to gather evidence on extensive dermatitis caused by HA injection, provide new perspectives and solutions for subsequent HA injections, and promote further research on the potential mechanisms of extensive skin inflammation and allergies caused by local HA injections.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11430385PMC
http://dx.doi.org/10.2147/CCID.S477847DOI Listing

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