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Background: Tobacco use is a known modifiable risk factor for postoperative complications and revision surgery after anterior cruciate ligament reconstruction (ACLR). Previous studies focus on tobacco as a broad categorization of traditional smoking, smokeless tobacco, and other forms of nicotine use. It is unclear if differences in the type of nicotine used lead to similar adverse outcomes after ACLR.

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The Tax Incidence and Tax Pass-Through of Smokeless Tobacco in the US.

Int J Environ Res Public Health

November 2024

Center for Tobacco Research, The Ohio State University Wexner Medical Center, 3650 Olentangy River Rd, Columbus, OH 43214, USA.

Background: States adopt different tax bases for smokeless tobacco (SLT), making tax incidence on SLT not directly comparable across states. In addition, how taxes are passed through to SLT prices among states that impose specific taxes, and whether the pass-through rates for SLT are affected by the uptake and evolution of e-cigarettes, is unknown.

Objective: This study will calculate the tax incidence on SLT and investigate how SLT taxes are passed to prices at the 25th, 50th, and 75th percentile levels, as well as whether these pass-through rates vary by e-cigarette uptake and evolution.

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Significance: Nicotine-containing products, labelled as being 'tobacco-free' nicotine (TFN), are marketed to consumers as alternatives to conventional tobacco products. Little is known about these emerging products and their contents.

Methods: Moisture, total nicotine and pH content were analysed in 70 commercially available TFN products, covering five different types (lozenges, chewing gum, loose leaf, toothpicks and pouches).

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Assessment of Abuse Liability and Nicotine Pharmacokinetics of glo Heated Tobacco Products in a Randomized, Crossover Study.

Eur J Drug Metab Pharmacokinet

November 2024

RAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA.

Article Synopsis
  • Heated tobacco products (HTPs) are considered potentially less harmful alternatives to traditional cigarettes, as they produce fewer toxicants.
  • A clinical study assessed the abuse liability (AL) of glo HTPs in two modes by comparing nicotine uptake and subjective effects to usual brand cigarettes and nicotine gum among healthy adult smokers.
  • Results indicated that glo HTPs led to significantly lower nicotine uptake and levels compared to regular cigarettes, suggesting they might be safer options for smokers.
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Background: This study aimed to evaluate and compare the efficacy of oral premedication with ibuprofen on the anesthetic efficacy of inferior alveolar nerve block (IANB) using 2% lignocaine and 1:100000 epinephrine in tobacco-chewing (TC) and non-tobacco-chewing (NTC) patients with symptomatic irreversible pulpitis (SIP) during nonsurgical endodontic intervention (NEI).

Methods: This multicenter, prospective, double-blind, two-arm parallel-group randomized controlled trial involving 160 patients was conducted for a period of 9 months. The patients were classified into the study (TC patients) and control (NTC patients) groups, which were subdivided into two subgroups 1 hour before the procedure based on oral premedication with tab ibuprofen 600 mg.

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