Genome sequencing of a non-tuberculosis species, isolated from a public pool, shows that the genome contains several genes for antibiotic resistance and anti-phage defense, which are absent from other related . Metagenomic binning also provided the genome of the accompanying phage, which is distinct from other mycobacterial phages.
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http://dx.doi.org/10.1128/mra.00896-24 | DOI Listing |
Cell Immunol
February 2025
Educational and Scientific Centre "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 2, Hlushkov Avenue, Kyiv 03022, Ukraine.
Bacteriophage-derived dsRNA (bp-dsRNA), also known as Larifan, is a poly-functional and wide-spectrum antiviral medication with potent interferonogenic activity. In the lungs of golden Syrian hamsters infected with SARS-CoV-2, Larifan substantially reduces viral load and decreases infection-induced pathological lesion severity. Alveolar macrophages (AM) are key sentinel cells in the lung, which play an important role in antiviral innate immune responses and, at the same time, can trigger infection-associated hyper-inflammatory response.
View Article and Find Full Text PDFACR Open Rheumatol
January 2025
Johns Hopkins University School of Medicine, Baltimore, Maryland.
Objective: Idiopathic inflammatory myopathies (IIMs) are a group of heterogeneous, systemic autoimmune diseases characterized by specific clinical features and, frequently, skeletal muscle inflammation. Specific subtypes of IIMs can be characterized by myositis-specific autoantibodies and are associated with distinct clinical phenotypes. Here, we focus on anti-melanoma differentiation-associated protein 5 (MDA5)-positive myositis and anti-signal recognition particle (SRP)-positive myositis, both of which exhibit seasonality but lack known environmental triggers.
View Article and Find Full Text PDFISME J
January 2024
Marine Microbiology Group (MMG), Department of Animal and Microbial Biodiversity, Mediterranean Institute for Advanced Studies (IMEDEA, CSIC-UIB), 07190 Esporles, Spain.
Virol J
October 2024
Restorative Dentistry Department of Dental Faculty, TABRIZ Medical University, Tabriz, Iran.
Dental infections, such as apical Periodontitis, periodontitis, and peri-implantitis (PI), are closely associated with specific bacterial species, including Streptococcus mutans (S. mutans), Porphyromonas gingivalis (P. gingivalis), and Fusobacterium nucleatum (F.
View Article and Find Full Text PDFMicrobiol Resour Announc
November 2024
College of Science and Technology, Bellevue University, Bellevue, Nebraska, USA.
Genome sequencing of a non-tuberculosis species, isolated from a public pool, shows that the genome contains several genes for antibiotic resistance and anti-phage defense, which are absent from other related . Metagenomic binning also provided the genome of the accompanying phage, which is distinct from other mycobacterial phages.
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