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| http://dx.doi.org/10.37201/req/050.2024 | DOI Listing |
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Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study.
BMC Med
December 2024
Department of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Background: Pregnancy is a complex biological process and serious complications can arise when the delicate balance between the maternal and semi-allogeneic fetal immune systems is disrupted or challenged. Gestational diabetes mellitus (GDM), pre-eclampsia, preterm birth, and low birth weight pose serious threats to maternal and fetal health. Identification of early biomarkers through an in-depth understanding of molecular mechanisms is critical for early intervention.
View Article and Find Full Text PDFUtilization of Institutional Maternal Delivery and Associated Factors among Rural Women: A Case Study of High Priority District of Himachal Pradesh.
Indian J Public Health
October 2024
Assistant Professor, Department of Economics, Guru Nanak Dev University College, Jalandhar, Punjab, India.
Background: Utilization of institutional maternal delivery is the cornerstone for the health of both mother and child which provides essential emergency care and reduces the risk of maternal and neonatal mortality. The aim of the current study is to analyze the perceptions of pregnant women regarding the place of maternal delivery in Lahaul and Spiti.
Materials And Methods: A cross-section study was conducted among 410 pregnant women in remote district of Himachal Pradesh.
Screening for pulmonary hypertension in pregnant women with sickle cell disease in sub-Saharan Africa.
AJOG Glob Rep
November 2024
Department of Family Medicine, Indiana University School of Medicine, Indianapolis, IN (Okuyemi).
Background: Sickle cell disease (SCD) has evolved from a condition predominantly fatal in childhood to a chronic illness impacting many adults, including women of reproductive age. For females with SCD, pregnancy represents one of the greatest health threats, exacerbating existing health challenges and introducing new risks. Despite advancements in healthcare, routine screening for existing complications like pulmonary hypertension (PH) remains inconsistent, particularly in low- and middle-income countries (LMICs), where the prevalence of SCD is highest.
View Article and Find Full Text PDFEpidemiological and molecular characteristics of carbapenem-resistant Klebsiella pneumoniae from pediatric patients in Henan, China.
Ann Clin Microbiol Antimicrob
November 2024
Henan International Joint Laboratory of Children's Infectious Diseases, Department of Neonatology, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Article Synopsis
- The study investigates the clinical and epidemiological characteristics of carbapenem-resistant Klebsiella pneumoniae (CRKP) specifically in pediatric patients from Henan, China, addressing a significant gap in research.
- A total of 108 CRKP isolates were collected, primarily from preterm infants in ICUs, with a noted association between ICU stays and increased mortality rates; the majority of isolates exhibited multi-drug resistance.
- The research found high levels of virulence factors and identified the most common sequence types and plasmid types, emphasizing the urgent need for monitoring and controlling these hypervirulent strains in children.
A systematic review and meta-analysis of heat exposure impacts on maternal, fetal and neonatal health.
Nat Med
November 2024
Wits Planetary Health Research Division, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Climate change has severe and wide-ranging health impacts, especially for vulnerable groups. Despite growing evidence of heat-associated adverse maternal and neonatal health outcomes, there remains a lack of synthesis quantifying associations and identifying specific risk periods. We systematically reviewed the literature on heat impacts on maternal, fetal and neonatal health and quantified impacts through meta-analyses.
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