Background And Aims: Colorectal polyps resected by cold snare polypectomy (CSP) are rarely diagnosed as colorectal cancer (CRC). We aimed to investigate the prevalence, clinical features, and prognosis of patients with CRC resected by CSP.
Subjects: Patients with colorectal polyps treated with CSP between 2018 and 2022 were enrolled and regularly followed up (median observation period: 30.6 months). Logistic regression analysis and decision tree analysis were employed to investigate the clinical features of the patients.
Results: A total of 5,064 colorectal polyps from 2,530 patients were resected by CSP. Of these, 0.24% were diagnosed as CRC; however, no patients died due to CRC. eGFR was an independent risk factor for the presence of CRC (unit 10, OR 0.716, 95%CI 0.525-0.973, P=0.0323) and its optimal cut-off value was 59.9 mL/min/1.73 m. The decision-tree analysis revealed that 2.03% of patients with creatinine ≥ 1.0 mg/dL had CRC.
Conclusion: CRC was diagnosed in 0.24% of the polyps; however, no patients died due to CRC. eGFR <60 mL/min/1.73 m and creatinine >1.0 mg/dL were associated with CRC. Thus, colorectal polyps should be carefully examined in patients with chronic kidney disease.
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http://dx.doi.org/10.2739/kurumemedj.MS7112002 | DOI Listing |
United European Gastroenterol J
December 2024
Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Introduction: Long-term data on metachronous advanced adenoma (AA) recurrence after endoscopic submucosal dissection (ESD) remain scarce, leading to a lack of a standardized surveillance strategy. This study aims to evaluate the long-term risk of recurrent AA after ESD.
Materials And Methods: A longitudinal retrospective cohort study with propensity-score matching was conducted in a tertiary hospital in Hong Kong.
Biomed Phys Eng Express
December 2024
Department of Electrical and Electronics Engineering, Kahramanmaras Sutcu Imam University, Kahramanmaraş Sütçü İmam Üniversitesi Kampüsü, Kahramanmaras, 46040, TURKEY.
Polyps are one of the early stages of colon cancer. The detection of polyps by segmentation and their removal by surgical intervention is of great importance for making treatment decisions. Although the detection of polyps through colonoscopy images can lead to multiple expert needs and time losses, it can also include human error.
View Article and Find Full Text PDFQuant Imaging Med Surg
December 2024
Department of Orthopedics, Peking Union Medical College Hospital, Beijing, China.
Background: Fast and accurate automatic segmentation of polyps in colonoscopy plays a crucial role in the early diagnosis and treatment of colon cancer. However, the current polyp segmentation algorithms based on deep neural networks suffer from the problems of larger models and lower segmentation accuracy. Meanwhile, achieving accurate segmentation of polyps is to improve the diagnostic efficiency of doctors, and this need motivates us to develop a set of lightweight models so that it can be easily embedded in clinical devices to meet the requirements of practical applications.
View Article and Find Full Text PDFBMC Cancer
December 2024
Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, Brazil.
Background: Colorectal cancer (CRC) is the second leading cause of cancer death worldwide. Early detection of precursor lesions or early-stage cancer could hamper cancer development or improve survival rates. Liquid biopsy, which detects tumor biomarkers, such as mutations, in blood, is a promising avenue for cancer screening.
View Article and Find Full Text PDFEndosc Int Open
December 2024
Gastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, Modena, Italy.
Colorectal endoscopic submucosal dissection (ESD) is often challenging and time-consuming. Prolonged sedation and general anesthesia are associated with a relevant risk of anesthesia-related adverse events (ARAEs), especially in elderly and frail patients. Spinal anesthesia (SA), a simple technique providing analgesia and motor block without systemic drug administration, has never been described in gastrointestinal endoscopy.
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