During 1981-1984 13 patients with clinically manifest postoperative fistulas (11 small intestinal and 2 colonic) were treated with parenteral hyperalimentation. The therapy only ensued on intensive care conditions and a spontaneous closure of the fistula was observed in 7 patients, in 2 patients closure ensued after relaparotomy and parenteral hyperalimentation the time before. Time of therapy was 18 days on an average, the amount of calories was 2,900-3,400 kcal/day.
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Cureus
December 2024
Internal Medicine, Nishtar Medical University, Multan, PAK.
Progressive familial intrahepatic cholestasis type 2 (PFIC2) is a rare genetic disorder characterized by severe intrahepatic cholestasis, which often manifests in infancy with progressive liver dysfunction. We present the case of a 3-month-old infant with a one-month history of jaundice, vomiting, and bloody stools, presenting a unique set of diagnostic challenges. Initial clinical and laboratory findings indicated significant liver dysfunction, prompting further imaging and genetic analysis.
View Article and Find Full Text PDFJ Multidiscip Healthc
January 2025
Clinical Nutrition Department, College of Applied Medical Sciences, Taibah University, Madinah, Kingdom of Saudi Arabia.
Background: Enteral Nutrition (EN) is the preferred method for providing nutritional support in intensive care units (ICUs) compared to parenteral nutrition (PN) due to its physiological advantages, safety profile, and cost-effectiveness compared to parenteral nutrition (PN). However, evidence suggests that EN might be associated with some complications. In this study, we aimed to identify the most common EN complications, as reported by healthcare professionals (HCPs) working in adult and paediatric ICUs (PICUs) in Saudi Arabia.
View Article and Find Full Text PDFJ Infect Dev Ctries
December 2024
Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Introduction: Since the dawn of the new millennium, Candida species have been increasingly implicated as a cause of both healthcare-associated as well as opportunistic yeast infections, due to the widespread use of indwelling medical devices, total parenteral nutrition, systemic corticosteroids, cytotoxic chemotherapy, and broad-spectrum antibiotics. Candida tropicalis is a pathogenic Candida species associated with considerable morbidity, mortality, and drug resistance issues on a global scale.
Methodology: We report a case of a 43-year-old man who was admitted to our hospital for further management of severe coronavirus disease 2019 (COVID-19) pneumonia.
Sci Rep
January 2025
Department of Neonatology, Children's Hospital of Soochow University, Suzhou, China.
This study investigated the correlation between quantitative echocardiographic characteristics within 3 days of birth and necrotizing enterocolitis (NEC) and its severity in preterm infants. A retrospective study was conducted on 168 preterm infants with a gestational age of < 34 weeks. Patients were categorized into NEC and non-NEC groups.
View Article and Find Full Text PDFJ Fungi (Basel)
January 2025
Department of Pediatric Bone Marrow Transplantation, Oncology and Hematology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.
Introduction: Posaconazole is recommended for prophylaxis in pediatric immunocompromised patients. Due to its variability in bioavailability and drug-to-drug interactions, EBMT recommends regimens based on therapeutic drug monitoring (TDM).
Materials And Methods: In total, 171 oncohematological pediatric patients on posaconazole prophylaxis were included.
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