Heterotopic splenic tissue is a rare phenomenon that can occur in the abdomen and mimic renal or gastrointestinal tumors on imaging. We describe a 24-year-old woman who initially presented with right flank pain, urinary frequency, intermittency, and nocturia. The patient was found to have a large mass distorting and displacing the right kidney, thought to be renal cell carcinoma with concern for metastasis to the ileocecal junction based on radiographic imaging. The patient underwent right radical nephrectomy with right adrenalectomy and partial colon resection to remove the ileocecal mass. Pathological examination revealed the renal mass to be splenic tissue and the ileocecal mass to be a dermoid cyst, with no evidence of renal malignancy. This is an exceptional demonstration of a right-sided splenic heterotopia of remarkably large size sufficient to cause symptoms of a mass effect.
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http://dx.doi.org/10.1177/10668969241283484 | DOI Listing |
Cureus
October 2024
Radiology, Al-Ahli Hospital, Hebron, PSE.
Merkel cell carcinoma (MMC) is a rare cutaneous neuroendocrine cancer that has the potential to metastasize. However, brain metastasis is infrequent in this type of cancer. We presented a case of a 55-year-old female patient with MCC who had a skin lesion on her right thigh.
View Article and Find Full Text PDFCancers (Basel)
September 2024
Department of Pediatrics Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Background: We generated a CD103DC vaccine using K7M3 OS cell lysates (cDCV) and investigated its ability to induce regression of primary tumors, established lung metastases, and a systemic immune response.
Methods: A bilateral tumor model was used to assess cDCV therapy efficacy and systemic immunity induction. K7M3 cells were injected into mice bilaterally.
J Community Hosp Intern Med Perspect
September 2024
Department of Internal Medicine, CAMC, Charleston, WV, 25304, USA.
Immune thrombocytopenia purpura (ITP) is defined as a platelet count lower than 100 × 10ˆ9/L, in the absence of known abnormalities in white blood cells, normal hemoglobin with generalized purpuric rash: making it a diagnosis of exclusion.1-2 ITP is due to destruction of platelets in the spleen via autoantibodies, resulting in reduced platelet counts.3 Though rare, ITP is linked with spontaneous retrobulbar hemorrhage (SRH).
View Article and Find Full Text PDFInt J Surg Pathol
September 2024
Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, USA.
Acta Chir Belg
September 2024
Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
Introduction: Chylopericardium represents a rare condition of chyle accumulation within the pericardial sac, caused by abnormal thoracic duct anatomy or prolonged increased pressure. Nothing by mouth (NPO) policy and total parenteral nutrition (TPN), even in combination with pericardial drainage, render only a temporary solution. Surgical intervention with thoracic duct ligation and creation of a pericardial window is believed to be the most effective treatment.
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