AI Article Synopsis
- Solitary fibrous tumor (SFT) is a type of spindle cell tumor linked to a specific genetic fusion (NAB2-STAT6) that can occur in any soft tissue, though pancreatic cases are rare.
- A 36-year-old man experienced abdominal pain and was found to have a mass in the pancreatic tail, but a biopsy did not confirm the diagnosis, leading to potential confusion with other pancreatic tumors.
- After robotic surgery to remove the tumor, the histopathology showed spindle cells, and specific immunostains confirmed SFT with a low chance of spreading, highlighting the effectiveness of robotic surgery for treatment.
Article Abstract
Solitary fibrous tumor (SFT) is a spindle cell tumor driven by the NAB2-STAT6 fusion gene. While it can originate from any soft tissue, primary SFT of the pancreas is rare with limited reports. A 36-year-old man came to our department due to abdominal pain. Computed tomography revealed a circular mass with weak peripheral enhancement and an internal cyst in the pancreatic tail. Diagnosis was not confirmed through endoscopic ultrasound-guided biopsy, and differential diagnoses included acinar cell carcinoma and pancreatic neuroendocrine tumor. A robotic distal pancreatectomy with splenectomy was performed, and the patient was discharged 11 days postoperatively. Histopathological examination showed an irregular arrangement of spindle cells, and immunohistochemical staining was positive for CD34 and STAT6, confirming an SFT diagnosis with low metastatic risk. Robotic surgery effectively managed this tumor.
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| http://dx.doi.org/10.1111/ases.13388 | DOI Listing |
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