Biosorption Ability of Pharmaceutically Active Compounds by sp. and .

Molecules

Department of Analytical Chemistry, Faculty of Chemistry and Pharmacy, University of Opole, Pl. Kopernika 11a, 45-040 Opole, Poland.

Published: September 2024

AI Article Synopsis

  • Drug overuse negatively impacts ecosystems, prompting efforts to reduce the environmental harm from pharmaceuticals.
  • This study explored the ability of two cyanobacteria species to biosorb specific drugs—paracetamol, diclofenac, and ibuprofen—using advanced analysis methods.
  • Results showed these cyanobacteria can effectively absorb paracetamol and diclofenac without toxicity, and may even promote growth and transformation of diclofenac into a dimer.

Article Abstract

Drug overuse harms the biosphere, leading to disturbances in ecosystems' functioning. Consequently, more and more actions are being taken to minimise the harmful impact of xenopharmaceuticals on the environment. One of the innovative solutions is using biosorbents-natural materials such as cells or biopolymers-to remove environmental pollutants; however, this focuses mainly on the removal of metal ions and colourants. Therefore, this study investigated the biosorption ability of selected pharmaceuticals-paracetamol, diclofenac, and ibuprofen-by the biomass of the cyanobacteria sp. and , using the LC-MS/MS technique. The viability of the cyanobacteria was assessed by determining photosynthetic pigments in cells using a UV-VIS spectrophotometer. The results indicate that both tested species can be effective biosorbents for paracetamol and diclofenac. At the same time, the tested compounds did not have a toxic effect on the tested cyanobacterial species and, in some cases, stimulated their cell growth. Furthermore, the sp. can effectively biotransform DCF into its dimer.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11434137PMC
http://dx.doi.org/10.3390/molecules29184488DOI Listing

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